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Modern wound dressings: Making and properties. II. Wound dressings containing immobilized proteolytic enzymes (a review)

  • Drug Synthesis Methods and Manufacturing Technology
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Abstract

Published data devoted to making and characterization of the properties of polymeric wound dressings with proteolytic action are reviewed. These data are indicative of individual dependence of the physicochemical properties, activity, and stability of each particular enzyme on the type of polymer matrix and the method of immobilization. In order to obtain wound dressings, which are active in physiological medium and retain their activity upon sterilization, it is necessary to optimize the composition and characteristics of a polymer matrix and the enzyme included into its structure.

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References

  1. Wounds and Wound Infections [in Russian], M. I. Kuzin and B. M. Kostyuchenok (eds.), Meditsina, Moscow (1981).

    Google Scholar 

  2. P. I. Tolstykh, V. K. Gostishchev, B. N. Arutyunyan, et al., Proteolytic Enzymes Immobilized on Fiber Materials: Use in Surgery [in Russian], Aistan, Yerevan (1990).

    Google Scholar 

  3. V. V. Korshak and M. I. Shtil’man, Using Polymers for Immobilization and Modification of Natural Compounds [in Russian], Nauka, Moscow (1984).

    Google Scholar 

  4. I. V. Berezin, N. L. Klyachko, A. V. Levashov, et al., Immobilized Enzymes: Biotechnology [in Russian], Vysshaya Shkola, Moscow (1987).

    Google Scholar 

  5. K. Martinek and I. V. Berezin, Usp. Khim., 5, 737–770 (1980).

    Google Scholar 

  6. V. A. Izumrudov and S. Kh. Lim, Vysokomol. Soedin., Ser. A, 44(5), 793–801 (2002).

    CAS  Google Scholar 

  7. S. P. Glyantsev, Author’s Abstract of Doctoral (Ph. D. Med. Sci.) Thesis [in Russian], Moscow (1993).

  8. V. N. Filatov and V. V. Ryl’tsev, Biologically Active Textile Materials [in Russian], InformElektro, Moscow (2002).

    Google Scholar 

  9. T. N. Yudanova, Author’s Abstract of Doctoral (Ph. D. Chem. Sci.) Thesis [in Russian], Moscow (2004).

  10. V. A. Alinovskaya, T. L. Yurkshtovich, V. A. Stel’makh, Abstracts of Papers. All-Union Sci. Conf. “ Problems in Modification of Natural and Synthetic Fiber-Forming Polymers”, MTI, Moscow (1991), pp. 25–26.

    Google Scholar 

  11. S. I. Khorunzhina, I. I. Shamolina, V. A. Khokhlova, and L. A. Vol’f, Prikl. Biokhim. Mikrobiol., 14(1), 11–14 (1978).

    PubMed  CAS  Google Scholar 

  12. S. I. Khorunzhina, Author’s Abstract of Candidate (Tech. Sci.) Thesis [in Russian], Leningrad (1977).

  13. L. S. Stepanova, Author’s Abstract of Candidate (Tech. Sci.) Thesis [in Russian], Leningrad (1979).

  14. L. A. Vol’f and V. A. Khokhlova, Production and Use of Fibers with Special Properties [in Russian], Mytishchi (1980).

  15. G. V. Lyubinskii, Ukr. Biokhim. Zh., 56(4), 390–394 (1984).

    CAS  Google Scholar 

  16. A. L. Komissarova, V. S. Yakubovich, P. I. Tolstykh, et al., Antibiot. Khimioterap., 10, 735–739 (1988).

    Google Scholar 

  17. Developments in Science and Technology [in Russian]. N. S. Egorov and V. D. Samuilov (eds.), Vysshaya Shkola, Moscow (1987), Issue 4, pp. 159–192.

    Google Scholar 

  18. R. N. Kil’deeva, Author’s Abstract of Doctoral (Ph. D. Chem. Sci.) Thesis [in Russian], Moscow (1998).

  19. W. Paul and C. P. Sharma, STP Pharma Sci., 10(1), 5–22 (2000).

    CAS  Google Scholar 

  20. Recent Achievements in Characterization of Chitin and Chitosan (Proc. 6th Int. Conf.) [in Russian], VNIRO, Moscow (2001), pp. 124–262.

  21. G. A. Vikhoreva, K. P. Khomyakov, I. Yu. Sakharov, and L. S. Gal’braikh, Khim. Volokna, 5, 34–37 (1995).

    Google Scholar 

  22. A. I. Dadashov, Author’s Abstract of Doctoral (Ph. D. Med. Sci.) Thesis [in Russian], Moscow (1994).

  23. A. D. Virnik, I. F. Skokova, T. N. Yudanova, et al., Prikl. Biokhim. Mikrobiol., 33(4), 428–432 (1997).

    PubMed  CAS  Google Scholar 

  24. Biologically Active Dressing Materials in Complex Therapy of Pyoinflammatory Wounds [in Russian], V. D. Fedorov and I. M. Chizh (eds.), Ministry of Public Health, Moscow (2000).

    Google Scholar 

  25. L. S. Stepanova, T. V. Kudryavtseva, I. I. Shamolina, and L. A. Volf, Abstracts of Papers. The 3rd All-Union Symp. “Production and Application of Immobilized Enzymes in Basic Research, Industry, and Medicine” [in Russian], VNIITIAF, Leningrad (1980), pp. 230.

    Google Scholar 

  26. V. E. Kaputskii and N. K. Grinyuk, Abstracts of Papers. The 6th All-Union Symp. “Synthetic Polymers for Medical Applications” [in Russian], Nauka, Alma-Ata (1983) pp. 107–109.

    Google Scholar 

  27. V. V. Ryl’tsev, V. N. Filatov, and R. Sh. Breitman, RF Patent No. 2 055 600, Byull. Izobret., No. 7 (1996).

  28. Medicinal Preparations Based on Modified Polysaccharides (Abstracts of Papers of Int. Symp.), NIIFKhP, Minsk (1998), pp. 53–54, 60–62.

  29. L. P. Istranov, R. K. Aboyants, and E. V. Istranova, RF Patent No. 2 118 176, Byull. Izobret., No. 24 (1998).

  30. L. I. Valuev, G. A. Sytov, A. A. Adamyan, et al., RF Patent No. 2 157 243, Byull. Izobret., No. 28 (2000).

  31. A. A. Adamyan, V. A. Kuznetsova, M. E. Rozenberg, et al., RF Patent No. 2 115 436, Byull. Izobret., No. 20 (1998).

  32. L. P. Istranov, R. K. Aboyants, N. I. Soloveva, and A. B. Shekhter, RF Patent No. 2 127 128, Byull. Izobret., No. 7 (1999).

  33. A. Ya. Sorokin, A. V. Rak, V. A. Kuznetsova, et al., Abstracts of Papers. The 6th All-Union Symp. “ Synthetic Polymers for Medical Applications” [in Russian], Nauka, Alma-Ata (1983), pp. 146–147.

    Google Scholar 

  34. B. G. Belen’kaya, V. N. Polevov, A. A. Adamyan, et al., Byull. Izobret., No. 29 (1998).

  35. A. A. Adamyan, V. N. Polevov, L. E. Kilimchuk, et al., RF Patent No. 2 031 661, Byull Izobret., No. 8 (1999).

  36. B. K. Gavrilyuk, I. B. Gavrilyuk, RF Patent No. 2 180 856, Byull. Izobret., No. 9 (2002).

  37. B. K. Gavrilyuk and I. B. Gavrilyuk, RF Patent No. 2 194 535, Byull. Izobret., No. 35 (2002).

  38. B. K. Gavrilyuk and V. B. Gavrilyuk, RF Patent No. 2 193 896, Byull. Izobret., No. 34 (2002).

  39. A. A. Podkolzin and K. G. Gurevich, Effect of Biologically Active Substances in Small Doses [in Russian], KMK, Moscow (2002).

    Google Scholar 

  40. T. N. Yudanova and I. V. Reshetov, Khim.-Farm. Zh., 40(2), 24–31 (2006).

    Google Scholar 

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Authors and Affiliations

  1. Moscow State Textile University, Moscow, Russia

    T. N. Yudanova

  2. Hertzen Cancer Research Institute, Moscow, Russia

    I. V. Reshetov

Authors
  1. T. N. Yudanova
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  2. I. V. Reshetov
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__________

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 8, pp. 24–28, August, 2006.

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Yudanova, T.N., Reshetov, I.V. Modern wound dressings: Making and properties. II. Wound dressings containing immobilized proteolytic enzymes (a review). Pharm Chem J 40, 430–434 (2006). https://doi.org/10.1007/s11094-006-0146-z

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  • DOI: https://doi.org/10.1007/s11094-006-0146-z

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