Abstract
With a view to optimizing of the quality control of sweetclover herbs and related preparations containing coumarins among the active substances, methods for the isolation and analysis of compounds of this class — in particular, coumarin and furocoumarin — are reviewed. The group of possible analytical methods includes gravimetric, titrimetric, photocolorimetric, and polarographic analysis, and the more recently developed spectroscopic (UV and IR), fluorimetric, and chromatographic (GC and HPLC) techniques.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 6, pp. 47–56, June, 2006.
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Lozhkin, A.V., Sakanyan, E.I. Natural coumarins: Methods of isolation and analysis. Pharm Chem J 40, 337–346 (2006). https://doi.org/10.1007/s11094-006-0123-6
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DOI: https://doi.org/10.1007/s11094-006-0123-6