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Embryonal tumor with abundant neuropil and true rosettes. A new entity or only variations of a parent neoplasms (PNETs)? This is the dilemma

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Summary

A rare embryonal brain tumor has been diagnosed in a 4-year-old boy. The mass, located at the pons and mesencephalon, has been histologically classified as an embryonal tumor containing abundant neuropil and true rosettes.

After surgical complete removal of the neoplasia, the child received intensive combined chemotherapy and radiotherapy. He is alive and free of disease at 34 months from surgery.

Difficulties in histological definition, possible suggestions for treatment proposals are discussed.

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Acknowledgements

The authors thank Mr Giuseppe Auteri for technical assistance.

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Authors and Affiliations

  1. Division of Hematology/Oncology, Department of Pediatrics, Catania University Hospital, Catania, Sicily, Italy

    M. La Spina, G. Russo & A. Di Cataldo

  2. Neurosurgical Department, General Hospital St Maria della Misericordia, Udine, Italy

    M. Skrap

  3. Department of Pathology and Laboratory Medicine, Division of Anatomic Pathology, General Hospital St Maria della Misericordia, Udine, Italy

    S. Pizzolitto

  4. Division of Pediatrics, University Hospital of Udine, Udine, Italy

    A. Nocerino

  5. Division of Hematology/Oncology, Department of Pediatrics, Padova University Hospital, Padova, Italy

    G. Perilongo

  6. Division of Hematology/Oncology, Department of Pediatrics, Catania University Hospital, 95123, Catania, Sicily, Italy

    M. La Spina

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  1. M. La Spina
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  2. S. Pizzolitto
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  3. M. Skrap
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  4. A. Nocerino
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  5. G. Russo
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  6. A. Di Cataldo
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  7. G. Perilongo
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Correspondence to M. La Spina.

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Spina, M.L., Pizzolitto, S., Skrap, M. et al. Embryonal tumor with abundant neuropil and true rosettes. A new entity or only variations of a parent neoplasms (PNETs)? This is the dilemma. J Neurooncol 78, 317–320 (2006). https://doi.org/10.1007/s11060-005-9105-x

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  • DOI: https://doi.org/10.1007/s11060-005-9105-x

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