Skip to main content

Advertisement

SpringerLink
Log in

Assessment of neurolymphomatosis by brachial plexus biopsy and PET/CT. Report of a case

  • Clinical Study
  • Published:
Journal of Neuro-Oncology Aims and scope Submit manuscript

Abstract

Objective: To report a biopsy-proven neurolymphomatosis in a young woman with previous non-Hodgkin’s lymphoma (NHL) of uterine cervix.

Patient: The patient presented with a painful brachial plexopathy and developed multiple cranial and spinal nerve palsies.

Methods and results: The diagnosis was achieved by an open brachial plexus biopsy. A PET/CT study was used to assess the full extent of the disease and showed involvement of additional cranial nerves and spinal nerve roots. A complete although short lasting clinical and radiological response was achieved by means of systemic high dose methotrexate treatment combined with rituximab and intra-CSF injections of cytarabine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. JM Baehring D Damek EC Martin RA Betensky FH Hochberg (2003) ArticleTitleNeurolymphomatosis Neuro-oncol 5 IssueID2 104–115 Occurrence Handle10.1215/S1522851702000170 Occurrence Handle12672282

    Article  PubMed  Google Scholar 

  2. T Kuntzer JA Lobrinus RC Janzer J Ghika J Bogousslavsky (2000) ArticleTitleClinicopathological and molecular biological studies in a patient with neurolymphomatosis Muscle Nerve 23 IssueID10 1604–1609 Occurrence Handle10.1002/1097-4598(200010)23:10<1604::AID-MUS21>3.0.CO;2-F Occurrence Handle1:STN:280:DC%2BD38%2FgsFOrsw%3D%3D Occurrence Handle11003800

    Article  CAS  PubMed  Google Scholar 

  3. A Quinones-Hinojosa RM Friedlander PJ Boyer TT Batchelor EA Chiocca (2000) ArticleTitleSolitary sciatic nerve lymphoma as an initial manifestation of diffuse neurolymphomatosis Case report and review of the literature. J Neurosurg 92 IssueID1 165–169 Occurrence Handle1:STN:280:DC%2BD3c%2FotFynsQ%3D%3D

    CAS  Google Scholar 

  4. PH Gordon DS Younger (1996) ArticleTitleNeurolymphomatosis Neurology 46 IssueID4 1191–1192 Occurrence Handle1:STN:280:BymA2szosVc%3D Occurrence Handle8780134

    CAS  PubMed  Google Scholar 

  5. MJ Bent Particlevan den HG Bruin Particlede GD Beun CJ Vecht (1995) ArticleTitleNeurolymphomatosis of the median nerve Neurology 45 IssueID7 1403–1405 Occurrence Handle7617204

    PubMed  Google Scholar 

  6. W Grisold M Drlicek K Jellinger (1993) ArticleTitleNeurolymphomatosis Neurology 43 IssueID8 1628–1629 Occurrence Handle1:STN:280:ByyA2MvlvF0%3D Occurrence Handle8351034

    CAS  PubMed  Google Scholar 

  7. R Diaz-Arrastia DS Younger L Hair G Inghirami AP Hays DM Knowles et al. (1992) ArticleTitleNeurolymphomatosis: a clinicopathologic syndrome re-emerges Neurology 42 IssueID6 1136–1141 Occurrence Handle1:STN:280:By2B1MzltlU%3D Occurrence Handle1340762

    CAS  PubMed  Google Scholar 

  8. JO Trelles C Urquiaga L Palomino L Trelles (1976) ArticleTitle[Human peripheral neurolymphomatosis (reticuloendothelial polyradiculoneuritis)] J Neurol Sci; 28 IssueID2 187–202

    Google Scholar 

  9. J Lhermitte LO Trelles (1934) ArticleTitleNeurolymphomatose peripherique humane Presse Med 42 289–292

    Google Scholar 

  10. A Pietrangeli M Milella S De Marco A Bartolazzi M Mottolese C Zompetta et al. (2000) ArticleTitleBrachial plexus neuropathy as unusual onset of diffuse neurolymphomatosis Neurol Sci 21 IssueID4 241–245 Occurrence Handle10.1007/s100720070083 Occurrence Handle1:STN:280:DC%2BD3M3gtlanuw%3D%3D Occurrence Handle11214664

    Article  CAS  PubMed  Google Scholar 

  11. C Schiepers JE Filmont J. Czernin (2003) ArticleTitlePET for staging of Hodgkin’s disease and non-Hodgkin’s lymphoma Eur J Nucl Med Mol Imaging 30 IssueIDSuppl 1 S82–S88 Occurrence Handle1:CAS:528:DC%2BD3sXktVynsrg%3D Occurrence Handle12719922

    CAS  PubMed  Google Scholar 

  12. A Trojan M Jermann C Taverna TF Hany (2002) ArticleTitleFusion PET-CT imaging of neurolymphomatosis Ann Oncol 13 IssueID5 802–805 Occurrence Handle10.1093/annonc/mdf057 Occurrence Handle1:STN:280:DC%2BD38zjtlWqtA%3D%3D Occurrence Handle12075752

    Article  CAS  PubMed  Google Scholar 

  13. SN Reske (2003) ArticleTitlePET and restaging of malignant lymphoma including residual masses and relapse Eur J Nucl Med Mol Imaging 30 IssueIDSuppl 1 S89–S96 Occurrence Handle12748829

    PubMed  Google Scholar 

  14. MJ Bent Particlevan den HG Bruin Particlede GM Bos dlR Brutel PA Sillevis Smitt (1999) ArticleTitleNegative sural nerve biopsy in neurolymphomatosis J Neurol 246 IssueID12 1159–1163 Occurrence Handle10.1007/s004150050535 Occurrence Handle10653308

    Article  PubMed  Google Scholar 

  15. T Batchelor K Carson A O’Neill SA Grossman J Alavi P New et al. (2003) ArticleTitleTreatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96-07 J Clin Oncol 21 IssueID6 1044–1049 Occurrence Handle10.1200/JCO.2003.03.036 Occurrence Handle1:CAS:528:DC%2BD2cXpsVGqsbc%3D Occurrence Handle12637469

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neuro-Oncology Service, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Felix Bokstein

  2. Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Odelyia Goor

  3. Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Boris Shihman & Miri Neufeld

  4. Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Shimon Rochkind

  5. Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Einat Even-Sapir & Ur Metser

  6. Division of Oncology, Tel Aviv Sourasky Medical Center, 6 Weizman st., Tel Aviv, Israel, 64239

    Felix Bokstein

Authors
  1. Felix Bokstein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Odelyia Goor
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Boris Shihman
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Shimon Rochkind
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Einat Even-Sapir
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ur Metser
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Miri Neufeld
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Felix Bokstein.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bokstein, F., Goor, O., Shihman, B. et al. Assessment of neurolymphomatosis by brachial plexus biopsy and PET/CT. Report of a case. J Neurooncol 72, 163–167 (2005). https://doi.org/10.1007/s11060-004-3389-0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11060-004-3389-0

Keywords

Search

Navigation