Abstract
Zygomycosis encompasses infections due to two distinct orders of fungi, Mucorales and Entomophthorales. With rare exception, Entomophthorales are restricted to tropical areas. By contrast, mucorales are ubiquitous opportunistic fungi, which play a crucial part in the natural decay process. In human pathology, they may be opportunistic agents and be responsible for rare infection called (Mucormycosis) zygomycosis. We report two cases of zygomycosis from Madhya Pradesh, Central India, one caused by Rhizopus oryzae in a diabetic patient and another caused by Rhizopus microsporus in an apparently healthy patient. The cases were diagnosed by direct microscopy, histopathological examination and culture. Both the patients were successfully treated with liposomal amphotericin B. Rhizopus microsporus is, for the first time reported from Madhya Pradesh, India, causing rhino-maxillary orbital zygomycosis.
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The authors wish to thank the Vice-Chancellor Rani Durgavati. University, for providing laboratory facilities and to The Director-General, Indian Council of Medical Research (ICMR), New Delhi, for awarding Research Associate Fellowship and Post Doctoral Research Associateship and Government of India, Ministry of Science and Technology, Department of Science and Technology SERC FAST Track Scheme, for Young Scientist to one of the author (S.R.N).
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Nawange, S.R., Singh, S.M., Naidu, J. et al. Zygomycosis Caused by Rhizopus microsporus and Rhizopus oryzae in Madhya Pradesh (M.P.) Central India: A Report of Two Cases. Mycopathologia 174, 171–176 (2012). https://doi.org/10.1007/s11046-012-9532-0
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DOI: https://doi.org/10.1007/s11046-012-9532-0