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Pseudotumoral Neuroparacoccidioidomycosis: One Case Report

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Abstract

Neuroparacoccidioidomycosis is the central nervous system involvement by Paracoccidioides brasiliensis, a condition that may be underdiagnosed and has been scarcely reported. We describe a case of neuroparacoccidioidomycosis in a diabetic male with antecedent of heavy cigarette smoking and alcohol abuse. Thirty years before, he lived in the Amazon area and exerted rural activities in more recent years. The patient’s main complaints were headache, visual deficit, hemiparesis, and weight loss. Imaging studies detected changes in the lungs and right adrenal gland, in addition to brain lesions. Paracoccidioides brasiliensis was found in tissue samples collected by the lung and brain biopsies. The patient is under ambulatory surveillance and in use of trimethoprim-sulfamethoxazole.

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Fig. 1

Abbreviations

NPCM:

Neuroparacoccidioidomycosis

PCM:

Paracoccidioidomycosis

(T-SM):

Trimethoprim-sulfamethoxazole

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Authors and Affiliations

  1. Catholic University Medical Course and Armed Forces Hospital (HFA), Brasilia, DF, Brazi

    Vitorino Modesto dos Santos

  2. Department of Internal Medicine from HFA, Armed Forces Hospital, Estrada do Contorno do Bosque s/n, Brasilia, DF, 70630-900, Brazil

    Vitorino Modesto dos Santos, Rogério Martins Xavier, Ernesto Misael Cintra Osterne & Maria de Worisch Ferreira Lopes

  3. Section of Pathology from HFA, Armed Forces Hospital, Estrada do Contorno do Bosque s/n, Brasilia, DF, 70630-900, Brazil

    Jacira Azevedo Cortes

  4. SMPW Quadra 14 Conjunto 2 Lote 7 Casa A, Brasilia, DF, 71745-140, Brazil

    Vitorino Modesto dos Santos

Authors
  1. Vitorino Modesto dos Santos
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  2. Rogério Martins Xavier
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  3. Jacira Azevedo Cortes
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  4. Ernesto Misael Cintra Osterne
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  5. Maria de Worisch Ferreira Lopes
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Correspondence to Vitorino Modesto dos Santos.

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dos Santos, V.M., Xavier, R.M., Cortes, J.A. et al. Pseudotumoral Neuroparacoccidioidomycosis: One Case Report. Mycopathologia 166, 155–158 (2008). https://doi.org/10.1007/s11046-008-9115-2

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  • DOI: https://doi.org/10.1007/s11046-008-9115-2

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