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Associated analysis of single nucleotide polymorphisms of IGF2 gene’s exon 8 with growth traits in Wuzhishan pig

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Abstract

A new SNP located in IGF-2 gene of Wuzhishan pig was detected while a C → T silent mutation at position 17 of exon 8 was detected by Single-Strand Conformational Polymorphism (SSCP). The value of polymorphism information content (PIC) indicated that this locus had intermediate polymorphism information content (0.25 < PIC < 0.5). The results of the fitness of Hardy-Weinberg equilibrium was in disequilibrium (P < 0.01). SAS analysis together with the multiple comparisons between polymorphisms and growth traits showed that: the differences of carcass weight (P = 0.024), withers height (P = 0.037) and chest girth (P = 0.025) in 10-month-old generation group were very remarkable.

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Acknowledgments

This experiment was supported by National Nonprofit Institute Research Grant of CATAS-TCGRI (grant PZS-013) and Communion Platform Constructional Project for Livestock & Poultry Germplasm Resource (grant 2005DKA21101) as well.

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Authors and Affiliations

  1. Tropical Crops Genetic Resources Institute, CATAS, 571737, Danzhou, Hainan, China

    Guanyu Hou, Dongjin Wang, Song Guan, Hongpu Zeng & Xianzhou Huang

  2. Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100094, Beijing, China

    Hongpu Zeng, Xianzhou Huang & Yuehui Ma

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  1. Guanyu Hou
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  2. Dongjin Wang
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  3. Song Guan
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  4. Hongpu Zeng
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  5. Xianzhou Huang
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  6. Yuehui Ma
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Correspondence to Yuehui Ma.

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Hou, G., Wang, D., Guan, S. et al. Associated analysis of single nucleotide polymorphisms of IGF2 gene’s exon 8 with growth traits in Wuzhishan pig. Mol Biol Rep 37, 497–500 (2010). https://doi.org/10.1007/s11033-009-9681-5

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  • DOI: https://doi.org/10.1007/s11033-009-9681-5

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