Abstract
Apolipoprotein E (apoE) genotypes were determined in 165 Saudis. The prevalence of genotype, E3/E3, E3/E4 and E4/E4 was found to be 71, 27 and 2% respectively. The E3/E3 was the most prevalent genotype among the Saudis followed by E3/E4. However, other genotypes E2/E2, E2/E3 and E2/E4 were absent showing the absence of E2 allele in the test population. The high frequencies of the E3 allele (0.845) and E3/E3 genotype (0.71) and absence of E2 allele in Saudis under study are similar to those reported earlier for Native Americans, Mexican-Americans, Mayans, Cayapa, Mazatecan Indians and Mexican Mestizos populations.
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Al-Khedhairy, A.A. Apolipoprotein E polymorphism in Saudis. Mol Biol Rep 31, 257–260 (2005). https://doi.org/10.1007/s11033-005-2713-x
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DOI: https://doi.org/10.1007/s11033-005-2713-x