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Intramolecular 1,3-dipolar cycloaddition reactions in the synthesis of complex annelated quinolines, α-carbolines and coumarins

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Abstract

In this study, we report the synthesis of several novel dihydroisoxazole-, tetrahydroisoxazole- and dihydropyrazole-fused pyrido[2,3-b]quinolines, α-carbolines, and pyrido[2,3-c]coumarins, respectively, from simple precursors and by exploring intramolecular 1,3-dipolar cycloaddition reactions involving nitrile oxides, nitrones, and nitrile imines as 1,3-dipoles.

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Authors and Affiliations

  1. Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat, 785006, Assam, India

    Swarup Majumder, Pallabi Borah & Pulak J. Bhuyan

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  1. Swarup Majumder
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  2. Pallabi Borah
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  3. Pulak J. Bhuyan
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Correspondence to Pulak J. Bhuyan.

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Majumder, S., Borah, P. & Bhuyan, P.J. Intramolecular 1,3-dipolar cycloaddition reactions in the synthesis of complex annelated quinolines, α-carbolines and coumarins. Mol Divers 16, 279–289 (2012). https://doi.org/10.1007/s11030-012-9358-1

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