Abstract
The stabilized phosphoranes, obtained from the three-component reaction between dialkyl acetylenedicarboxylates and urea or N-methylurea in the presence of triphenylphosphine, undergo a smooth reaction in boiling toluene to produce iminophosphoranes in good yields. Under the same reaction conditions, the phosphorane obtained from N-methylurea and dimethyl acetylenedicarboxylate yields methyl 1-methyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylate.
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Yavari, I., Zabarjad-Shiraz, N. Three-component reaction between triphenylphosphine, dialkyl acetylenedicarboxylates and urea or N-methylurea. Mol Divers 10, 23–27 (2006). https://doi.org/10.1007/s11030-006-8696-2
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DOI: https://doi.org/10.1007/s11030-006-8696-2