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Solid state studies on molecular inclusions of Lippia sidoides essential oil obtained by spray drying

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Abstract

Inclusion complexes of Lippia sidoides essential oil and β-cyclodextrin were obtained by slurry method and its solid powdered form was prepared using spray drying. The influence of the spray drying, as well as the different essential oil:β-cyclodextrin ratio on the characteristics of the final product was investigated. With regard to the total oil retention 1:10 mass/mass ratio as optimal was found between the essential oil and β-cyclodextrin.

Thermoanalytical techniques (TG, EGD, TG-MS) were used to support the formation of inclusion complex and to examine their physicochemical properties after accelerated storage conditions. It may be assumed that the thermal properties of the complexes were influenced not only by the different essential oil/ β-cyclodextrin ratio but also by the storage conditions. In the aspect of their thermal stabilities, complex prepared with 1:10 m/m ratio (essential oil:β-cyclodextrin) was the most stable one.

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References

  1. T. L. G. Lemos, F. J. A. Matos, J. W. Alencar and A. A. Craveiro, Phytother. Res., 4 (1990) 82.

    Article  Google Scholar 

  2. F. J. A. Matos and F. Oliveira, Rev. Bras. Farm., 7 (1998) 84.

    Google Scholar 

  3. R. O. S. Fontenelle, S. M. Morais, E. H. S. Brito, M. R. Kerntopf, R. S. N. Brilhante, R. A. Cordeiro, A. R. Tomé, M. G. R. Queiroz, N. R. F. Nascimento, J. J. C. Sidrim and M. F. G. Rocha, J. Antimicrob. Chemoth., 59 (2007) 934.

    Article  CAS  Google Scholar 

  4. H. Loza-Tavera, Adv. Exp. Med. Biol., 464 (1999) 49.

    CAS  Google Scholar 

  5. O. Bekers, E. V. Uijendaal, A. Beijnen and W. J. M. Undeberg, Drug Dev. Ind. Pharm., 17 (1991) 1503.

    Article  CAS  Google Scholar 

  6. J. Szejtli, Chem. Rev., 98 (1998) 1743.

    Article  CAS  Google Scholar 

  7. L. P. Fernandes, Zs. Éhen, T. F. Moura, Cs. Novák and J. Sztatisz, J. Therm. Anal. Cal., 78 (2004) 557.

    Article  CAS  Google Scholar 

  8. A. P. Martins, A. A. Craveiro, M. I. L. Machado, F. N. Raffin, T. F. Moura, Cs. Novák and Zs. Éhen, J. Therm. Anal. Cal., 88 (2007) 363.

    Article  CAS  Google Scholar 

  9. K. G. H. Desai and H. J. Park, Dry Technol., 23 (2005) 1361.

    Article  CAS  Google Scholar 

  10. E. M. Martin Del Valle, Process Biochem., 39 (2004) 1033.

    Article  Google Scholar 

  11. F. Giordano, Cs. Novák and J. R. Moyano, Thermochim. Acta, 380 (2001) 123.

    Article  CAS  Google Scholar 

  12. Zs. Éhen, F. Giordano, J. Sztatisz, L. Jicsinszky and Cs. Novák, J. Therm. Anal. Cal., 80 (2005) 419.

    Article  Google Scholar 

  13. Cs. Novák, Zs. Éhen, M. Fodor, L. Jicsinszky and J. Orgoványi, J. Therm. Anal. Cal., 84 (2006) 693.

    Article  Google Scholar 

  14. I. Padukka, B. R. Bhandari and B. R. D’Arcy, J. Food Comp. Anal., 13 (2000) 59.

    Article  CAS  Google Scholar 

  15. R. P. Adams. Carol Stream, IL: Allured Publishing, 2001.

    Google Scholar 

  16. X. D. Liu, T. Furuta, H. Yoshii, P. Linko and W. J. Coumans, Biosci. Biotechnol. Biochem., 64 (2000) 1608.

    Article  CAS  Google Scholar 

  17. B. R. Bhandari, B. R. D’Arcy and L. L. Thi Bich, J. Agr. Food Chem., 46 (1998) 1494.

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo Av. do Café, s/n°, Ribeirão Preto - SP, Brazil

    Luciana P. Fernandes & W. P. Oliveira

  2. Institute of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, 1111, Budapest, St. Gellért ter 4, Hungary

    J. Sztatisz

  3. Materials Structure and Modeling Research Group of the Hungarian Academy of Sciences, Budapest University of Technology and Economics, 1111, Budapest, St. Gellért ter 4, Hungary

    I. M. Szilágyi

  4. Hungarian Academy of Sciences, Budapest University of Technology and Economics, Research Group of Technical Analytical Chemistry, 1111, Budapest, St. Gellért ter 4, Hungary

    Luciana P. Fernandes & Cs. Novák

Authors
  1. Luciana P. Fernandes
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  2. W. P. Oliveira
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  3. J. Sztatisz
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  4. I. M. Szilágyi
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  5. Cs. Novák
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Correspondence to Cs. Novák.

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Fernandes, L.P., Oliveira, W.P., Sztatisz, J. et al. Solid state studies on molecular inclusions of Lippia sidoides essential oil obtained by spray drying. J Therm Anal Calorim 95, 855–863 (2009). https://doi.org/10.1007/s10973-008-9149-1

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  • DOI: https://doi.org/10.1007/s10973-008-9149-1

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