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Thermal behaviour of new N,N-dimethylbiguanide complexes having selective and effective antibacterial activity

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Abstract

The complexes of the type M(HDMBG)2(CH3COO)2·nH2O ((1) M:Mn, n=1.5; (2) M:Ni, n=0; (3) M:Cu, n=2; (4) M:Zn, n=2; DMBG: N,N-dimethylbiguanide) present in vitro antimicrobial activity. The thermal analysis has evidenced the thermal intervals of stability and also the thermodynamics effects that accompany them. The different nature of the ligands generates a different thermal behaviour for the complexes. The thermal transformations are complex processes according to TG and DTG curves including dehydration, oxidative condensation of –C=N– units as well as thermolysis processes. The final products of decomposition are the most stable metal oxides.

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References

  1. P Hubberstey U Suksangpanya (2004) Struct. Bond. 111 33 Occurrence Handle1:CAS:528:DC%2BD2cXktVOms7c%3D

    CAS  Google Scholar 

  2. AJJ Wood CJ Bailey RC Turner (2003) New England J. Med. 334 574

    Google Scholar 

  3. P Pignard (1962) Ann. Biol. Clin. 20 325 Occurrence Handle1:CAS:528:DyaF38XktlKltLk%3D

    CAS  Google Scholar 

  4. G Siest F Roos JJ Gabou (1963) Bull. Soc. Pharm. Nancy 58 29 Occurrence Handle1:CAS:528:DyaF2cXhsFOiuw%3D%3D

    CAS  Google Scholar 

  5. F Bentefrit G Morgant B Viossat S Leonce N Guilbaud A Pierre G Atassi D Nguyen-Huy (1997) J. Inorg. Biochem. 68 53 Occurrence Handle10.1016/S0162-0134(97)81616-9 Occurrence Handle1:CAS:528:DyaK2sXmt1Wqs74%3D

    Article  CAS  Google Scholar 

  6. R Olar M Badea E Cristurean V Lazar R Cernat C Balotescu (2005) J. Therm. Anal. Cal. 80 351

    Google Scholar 

  7. P Lemoine M Chiadmi V Bissery A Tomas B Viossat (1996) Acta. Cryst. C52 1430

    Google Scholar 

  8. M Zhu L Lu X Jin P Yang (2002) Acta. Cryst. C58 158

    Google Scholar 

  9. F Bentefrit A Tomas G Morgan D Nguyen-Huy P Lemoine B Viossat (2002) Z. Kristallogr. 217 1

    Google Scholar 

  10. B Viossat A Tomas D Nguyen-Huy (1995) Acta. Cryst. C51 213 Occurrence Handle1:CAS:528:DyaK2MXkt1Wqu74%3D

    CAS  Google Scholar 

  11. M Zhu L Lu P Yang X Jin (2002) Acta. Cryst. E58 217

    Google Scholar 

  12. M Zhu L Lu P Yang X Jin (2002) Acta. Cryst. C58 272

    Google Scholar 

  13. L Lu M Zhu P Yang (2004) Acta. Cryst. C60 18

    Google Scholar 

  14. P Lemoine A Tomas B Viossat D Nguyen-Huy (1994) Acta. Crystallogr. C50 1437

    Google Scholar 

  15. Z He M Zhu G Ma (2002) Acta. Cryst. E58 647

    Google Scholar 

  16. R. Olar, M. Badea, E. Iorgulescu, N. M. Grecu, V. Lazar and C. Balotescu, J. Inorg. Biochem., (2006) in press

  17. K Nakamoto et al. (1986) Infrared and Raman Spectra of Inorganic and Coordination Compounds Wiley New York 253

    Google Scholar 

  18. JE Sheats RS Czernuszewicz GC Dismukes AL Rheingold V Petrouleas JA Stubbe WH Armstrong RH Beer SJ Lippard (1987) J. Am. Chem. Soc. 109 1435 Occurrence Handle10.1021/ja00239a025 Occurrence Handle1:CAS:528:DyaL2sXpsV2jtg%3D%3D

    Article  CAS  Google Scholar 

  19. T Vlase G Vlase A Chiriac N Doca (2003) J. Therm. Anal. Cal. 72 839 Occurrence Handle1:CAS:528:DC%2BD3sXmtVKku7Y%3D

    CAS  Google Scholar 

  20. P Tarte (1963) Spectrochim. Acta 19 49 Occurrence Handle1:CAS:528:DyaF3sXisVCgug%3D%3D

    CAS  Google Scholar 

  21. R Olar M Badea D Marinescu E Iorgulescu S Stoleriu (2005) J. Therm. Anal. Cal. 80 363 Occurrence Handle1:CAS:528:DC%2BD2MXjvVCmtr8%3D

    CAS  Google Scholar 

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Authors and Affiliations

  1. Faculty of Chemistry, Department of Inorganic Chemistry, University of Bucharest, Bucharest, Romania, 050663 Sector 5, 90-92 Panduri Street

    Olar Rodica, Badea Michaela, Cristurean E., Parnau C. & Marinescu D.

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  1. Olar Rodica
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  2. Badea Michaela
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  3. Cristurean E.
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  4. Parnau C.
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  5. Marinescu D.
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Correspondence to Olar Rodica.

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Olar, R., Badea, M., Cristurean, E. et al. Thermal behaviour of new N,N-dimethylbiguanide complexes having selective and effective antibacterial activity. J Therm Anal Calorim 84, 53–58 (2006). https://doi.org/10.1007/s10973-005-7177-7

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  • DOI: https://doi.org/10.1007/s10973-005-7177-7

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