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Bioactive textiles by sol–gel immobilised natural active agents

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Abstract

The sol–gel immobilisation and controlled release of various bioactive liquids (BL) from within modified silica coatings were investigated, in order to evaluate the suitability of functionalised textiles for the following applications: (1) skin-friendly textiles with antimicrobial and antiallergic effects due to immobilised natural oils such as evening primrose and perilla oil; (2) textiles for therapeutic treatment of the respiratory tract by means of immobilised mixtures of high volatility natural agents such as eucalyptol, camphor and menthol. Results indicating the antimicrobial properties, washfastness and medical activity of the bioactive textiles are presented. Of note is the transdermal resorption of the BL from the sol–gel coated textiles, determined by the time-dependent concentration of cineol, camphor and menthol in the air exhaled by test subjects after the application of coated textiles. When compared to the application of an ointment, not only does the use of coated textiles offer a more continuous and prolonged release of the embedded BL, but it is also more convenient.

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Notes

  1. This incorporation of liquids into porous oxide matrices has a famous historical model: incorporating liquid nitroglycerin into microporous kieselguhr forms dynamite.

  2. Therefore, silver-coated textiles suppress S. aureus colonization and toxin formation, thus damping the inflammatory reaction (see [9]).

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Acknowledgements

The research was supported by the German Federal Ministry of Economics and Labour, project PRO INNO II KF 0035301UL4 and by the company iSKiA GmbH & Co. KG Medizintechnik Harsleben/Germany.

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Authors and Affiliations

  1. Department of Functional Coatings, GMBU e.V, P.O. Box 520165, 01317 , Dresden, Germany

    Helfried Haufe, Kerstin Muschter & Horst Böttcher

  2. Institute of Clinical Pharmacology, TU Dresden, Fiedlerstraße 27, 01307 , Dresden, Germany

    Joachim Siegert

Authors
  1. Helfried Haufe
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  2. Kerstin Muschter
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  3. Joachim Siegert
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  4. Horst Böttcher
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Correspondence to Horst Böttcher.

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Haufe, H., Muschter, K., Siegert, J. et al. Bioactive textiles by sol–gel immobilised natural active agents. J Sol-Gel Sci Technol 45, 97–101 (2008). https://doi.org/10.1007/s10971-007-1636-5

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  • DOI: https://doi.org/10.1007/s10971-007-1636-5

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