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Reduced dose uncertainty in MRI-based polymer gel dosimetry using parallel RF transmission with multiple RF sources

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Abstract

In this work, we present the feasibility of using a parallel RF transmit with multiple RF sources imaging method (MultiTransmit imaging) in polymer gel dosimetry. Image quality and B1 field homogeneity was statistically better in the MultiTransmit imaging method than in conventional single source RF transmission imaging method. In particular, the standard uncertainty of R 2 was lower on the MultiTransmit images than on the conventional images. Furthermore, the MultiTransmit measurement showed improved dose resolution. Improved image quality and B1 homogeneity results in reduced dose uncertainty, thereby suggesting the feasibility of MultiTransmit MR imaging in gel dosimetry.

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Acknowledgments

This study was supported by the program of Basic Atomic Energy Research Institute (BAERI) (2009-0078390) and a grant (2012-007883) from the Mid-career Researcher Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (MSIP) of Korea. This study was conducted using a whole-body 3T MRI scanner at the Ochang Center of the Korea Basic Science Institute (KBSI-#E34600).

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Authors and Affiliations

  1. Department of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University, Seoul, Republic of Korea

    Sang-Young Kim, Jung-Hoon Lee, Jin-Young Jung, Do-Wan Lee, Seu-Ran Lee & Bo-Young Choe

  2. Center of Magnetic Resonance Research, Korea Basic Science Institute, Ochang, Chungbuk, Republic of Korea

    Hyeon-Man Baek

  3. Department of Radiation Oncology, Samsung Medical Center, Seoul, Republic of Korea

    Dae-Hyun Kim

  4. Department of Radiological Science, The Shingu University College of Korea, Seongnam, Republic of Korea

    Jung-Whan Min

  5. Department of Pediatrics and Molecular Imaging Program at Stanford, Standford University, Palo Alto, CA, USA

    Ji-Yeon Park

  6. Department of Bio-Analytical Science, Korea University of Science and Technology, Daejeon, Republic of Korea

    Hyeon-Man Baek

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  1. Sang-Young Kim
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Correspondence to Bo-Young Choe.

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Kim, SY., Baek, HM., Lee, JH. et al. Reduced dose uncertainty in MRI-based polymer gel dosimetry using parallel RF transmission with multiple RF sources. J Radioanal Nucl Chem 302, 533–541 (2014). https://doi.org/10.1007/s10967-014-3232-9

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