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Producing radioisotopes in power reactors

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Abstract

The demand of radioisotopes is rising due to wide-ranging applications in industry, agriculture, medicine and in research. Two sources of artificial radioisotopes are accelerators and reactors. The reactor offers large volume for irradiation, simultaneous irradiation of different samples and economy of production, whereas accelerators are generally used to produce those isotopes which can not be produced by reactor. Radioisotope production started on a significant scale in several countries with the commissioning of research reactors starting from the late 1950s. The period from 1950 to 1970 saw construction of a large number of research reactors with multiple facilities. After 1980, because of the decommissioning of many old ones, the number of operating reactors has been steadily decreasing. The research reactors used for radioisotope production could be broadly classified into swimming pool type and tank type reactors. CANDU power reactors currently produce many millions of curies per year of 60Co for MDS Nordion’s use in industry and commerce. Studies related to production of other isotopes in power reactors have also been performed. Indeed, while a very few reactors have come online in the past decade, many more have been retired or may retire in coming years. After failure of MAPLE project, there has been unwillingness to built new reactors. Activism and politics has made it so difficult to build new reactors that we are left to use only the reactors we inherited from a nuclear era. Many design considerations and requirements for the production of isotopes in power reactors must be assessed, such as; operator and public safety, minimum impact on station efficiency and reactor operations, shielding requirements during reactor operation with target adjusters and removal of the target adjusters from core, transportation within the station, and finally the processing and shipment off-site. Use of power reactors for isotope production is reviewed.

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References

  1. Lawrence EO, Livingston MS (1932) Phys Rev 40:19

    Article  CAS  Google Scholar 

  2. Curie I, Joliot-Curie F (1934) Nature 133:201

    Article  Google Scholar 

  3. Sood DD (2003) J Radioanal Nucl Chem 257(1):219

    Article  CAS  Google Scholar 

  4. Troyer GL, Schenter RE (2009) J Radioanal Nucl Chem 282:243

    Article  CAS  Google Scholar 

  5. Han HS, Cho WK, Park UJ, Hong YD, Park KB (2003) J Radioanal Nucl Chem 257(1):47

    Article  CAS  Google Scholar 

  6. Ball G (2003) J Radioanal Nucl Chem 257(1):65

    Article  CAS  Google Scholar 

  7. Knapp FF(Russ) Jr, Mirzadeh S, Beets AL, Du M (2005) J Radioanal Nucl Chem 263(2): 503

    Google Scholar 

  8. Bokhari TH, Mushtaq A, Khan IU (2010) J Radioanal Nucl Chem 284(2):265

    Article  CAS  Google Scholar 

  9. IAEA, TECDOC-1340 (2003) Manual for reactor produced radioisotopes, International Atomic Energy Agency, Vienna

  10. Takács S, Szecs Z, Tárkányi F, Hermanne A, Sonck M (2003) J Radioanal Nucl Chem 257(1):195

    Article  Google Scholar 

  11. IAEA, TRS-465 (2008) Cyclotron produced radionuclides: principles and practice, International Atomic Energy Agency, Vienna

  12. Preliminary report on supply of radioisotopes for medical use and current developments in nuclear medicine, SANCO/C/3/HW D(2009) Rev. 8, 30 October 2009

  13. Haubner R (2010) Radiother Oncol 96:280

    Article  Google Scholar 

  14. Mushtaq A (2009) Ann Nucl Med 23:321

    Article  Google Scholar 

  15. Coenen HH, Elsinga PH, Iwata R, Kilbourn MR, Pillai MR, Rajan MG, Wagner HN Jr, Zaknun JJ (2010) Nucl Med Biol 37(7):727

    Article  CAS  Google Scholar 

  16. Mushtaq A (2010) Ann Nucl Med 24:759

    Article  Google Scholar 

  17. IAEA Research Reactor Database (2011) (http://www.iaea.org/worldatom/rrdb/). Accessed 30 Sept 2011

  18. Nuclear technology review (2011), item 4 of the provisional agenda, (GOV/2011/2) report by the director general, IAEA Vienna, Date: 17 February 2011

  19. NEA No. 5293, OECD (2005) Beneficial uses and production of isotopes, 2004 update

  20. James AS, Frederick J (1995) (eds) Managing isotopes for medicine and the life sciences, Committee on Biomedical Isotopes, Institute of Medicine, http://www.nap.edu/catalog/4818.html

  21. Power Reactor Information System-PRIS (2011) http://www.iaea.org/programmes/a2/. Accessed 30 Sept 2011

  22. World Nuclear Industry Handbook (2010) Nuclear engineering international. www.getthatmag.com/power.html

  23. RBMK (2011) http://en.wikipedia.org/wiki/RBMK

  24. OECD (2010) The supply of medical radioisotopes: review of potential molybdenum-99/technetium-99m production technologies, Nuclear Energy Agency, Organization for Economic Co-operation and Development

  25. Zykov MP, Romanovskii VN, Wester DW, Bartenev SA, Korpusov GV, Filyanin AT, Babain VA, Kodina GE, Strelkov SA, Erofeev SP, Firsin NG (2001) Radiochemistry 43(3):297

    Article  CAS  Google Scholar 

  26. GE-HITACHI (2010) GE Hitachi nuclear energy to deliver life saving isotope molybdenum-99 using alternative to highly enriched uranium, press release 25 January, 2010. www.ge-energy.com/about/press/en/2010_press/012510.htm

  27. Dadachova K, La Riviere K, Anderson P (1999) J Radioanal Nucl Chem 240(3):935

    Article  CAS  Google Scholar 

  28. Shikata E, Iguchi A (1986) J Radioanal Nucl Chem 102(2):533

    Article  CAS  Google Scholar 

  29. Talley DG, Bourcier SC, McDonald MJ, Longley SW, Parma EJ (1998) J Radioanal Nucl Chem 236(1–2):169

    Article  CAS  Google Scholar 

  30. Cuttler JM (2010) Producing molybdenum-99 in CANDU reactors. In: 31st Annual conference of the Canadian nuclear society, Montréal, Québec, May 24–27, 2010

  31. Malkoske GR, Slack J, Norton JL, (2001) Cobalt-60 production in CANDU reactors http://www.nuclearfaq.ca/malkoskie_cobalt_paper.pdf

  32. Artemov VG, Elshin AV, Ivanov AS, Gorbunov EK, Ikonnikov RV, Pimenov AN (2010) At Energy 108(2):136

    Article  CAS  Google Scholar 

  33. Artemov VG, Elshin AV, Ivanov AS, Gorbunov EK, Ikonnikov RV, Pimenov AN (2010) At Energy 108(1):59

    Article  CAS  Google Scholar 

  34. Coppell D, Latham I, Nazarov M (2004) Radiat Phys chem 71(1–2):573

    Article  CAS  Google Scholar 

  35. George JR, Kushwah R, Sastry KVS (2009) J Med Phys 34(3):180

    Article  Google Scholar 

  36. Borshchev VP, Zhukov IV, Mel’nikov OP, Rozhdestvenskii MI, Cherkashov YuM, Burlakov EV, Kvator VM, Gorbunov EK, Lebedev VI, Fursov AN, Shevchenko VG, Kuznetsov VYu, Mironov YuI, Romanenko VI, Ryakhovskikh VI (2003) Atomic Energy 95(6):856

    Article  CAS  Google Scholar 

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Mushtaq, A. Producing radioisotopes in power reactors. J Radioanal Nucl Chem 292, 793–802 (2012). https://doi.org/10.1007/s10967-011-1537-5

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