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Mechanical performances, in-vitro antibacterial study and bone stress prediction of ceramic particulates filled polyether ether ketone nanocomposites for medical applications

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Abstract

Polyether ether ketone (PEEK) and PEEK composites are viable candidates for dental and ortho implants due to their superior properties. This research aims to develop the functionalized ceramic nanoparticles such as TiO2 (T-NPs) and SiO2 (S-NPs) reinforced biopolymer nanocomposites by injection moulding. The morphologies of fabricated composite group were analysed by FE-SEM. The effect of T-NPs, S-NPs, and combined effect of TS-NPs of different wt.% reinforcements (4, 8, 12, 16, and 20 wt.%) with PEEK matrix on mechanical properties such as tensile, flexural, compressive, and shore D hardness had been investigated. The excellent mechanical strengths were obtained in 16 wt.% T/PEEK, 12 wt.% S/PEEK, and 16 wt.% TS/PEEK group. Then, the in-vitro antibacterial property of these selected composite group was investigated and found improved antibacterial activity compared to neat PEEK. Four different thread profiles were selected and analysed using 3D-FEM to reduce the stress distribution at bone-implant contact region. The minimum stress distribution range was achieved in the cortical bone model as 0.11–1.74 MPa due to trapezium profile threaded implants. Thus, the developed composites were found to be promising material for medical implant applications.

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  1. Department of Mechanical Engineering, Government College of Technology, Coimbatore, 614 013, Tamil Nadu, India

    Aezhisai Vallavi Muthusamy Subramanian & Mugilan Thanigachalam

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  1. Aezhisai Vallavi Muthusamy Subramanian
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Muthusamy Subramanian, A.V., Thanigachalam, M. Mechanical performances, in-vitro antibacterial study and bone stress prediction of ceramic particulates filled polyether ether ketone nanocomposites for medical applications. J Polym Res 29, 318 (2022). https://doi.org/10.1007/s10965-022-03180-6

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