Abstract
Psychological distress has been inconsistently associated with sexual risk behavior in youth, suggesting additional factors, such as substance use, may explain this relationship. The mediating or moderating role of substance use on the relationship between psychological distress and sexual risk behaviors was prospectively examined over the four high school years in a sample of urban youth (N = 850; 80% African American; 50% female). Growth curve modeling was used to estimate changes in sexual risk across adolescence and to test its association to psychological distress symptoms and frequency of substance use. Substance use was associated with psychological distress. Greater psychological distress was associated with increased sexual intercourse frequency, decreased condom use, and increased number of partners. Substance use fully mediated the relationship between psychological distress and intercourse frequency and condom use, and partially mediated the relationship between psychological distress and number of partners. We found no differences in mediation by sex or race/ethnicity and no evidence to support moderation of psychological distress and substance use on sexual risk. Findings suggest that psychological distress is associated with sexual risk because youth with greater psychological distress are also more likely to use substances. Practical implications for adolescent HIV/STI prevention are discussed.
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Angold, A., Costello, E. J., & Erkanli, A. (1999). Comorbidity. Journal of Child Psychology and Psychiatry, 40, 57–87.
Armstrong, T. D., & Costello, E. J. (2002). Community studies of adolescent substance use, abuse or dependence and psychiatric comorbidity. Journal of Consulting and Clinical Psychology, 70, 1224–1239.
Bachanas, P., Morris, M., Lewis-Gess, J., Sarett-Cuasay, E. J., Flores, A. L., Sirl, K., et al. (2002a). Psychological adjustment, substance use, HIV knowledge, and risky sexual behavior in at-risk minority females: Developmental differences during adolescence. Journal of Pediatric Psychology, 27(4), 373–384.
Bachanas, P., Morris, M., Lewis-Gess, J., Sarett-Cuasay, E. J., Sirl, K., Ries, J. K., et al. (2002b). Predictors of risky sexual behavior in African-American girls: Implications for prevention interventions. Journal of Pediatric Psychology, 27(6), 519–530.
Bauermeister, J. A., Elkington, K. S., Brackis-Cott, E., Dolezal, C., & Mellins, C. (2009a). Sexual behavior and perceived peer norms: Comparing perinatally infected and affected youth. Journal of Youth and Adolescence, 38(8), 1110–1122.
Bauermeister, J. A., Zimmerman, M., Barnett, T. E., & Caldwell, C. (2007). Working in high school and adaptation in the transition to young adulthood among African American youth. Journal of Youth and Adolescence, 36, 877–890.
Bauermeister, J. A., Zimmerman, M., Gee, G., Caldwell, C., & Xue, Y. (2009b). Work and sexual trajectories among African American youth. Journal of Sex Research, 46(4), 290–300.
Birmaher, B., Ryan, N., Williamson, D., Brent, D. A., Kaufman, J., Dahl, R. E., et al. (1996). Childhood and adolescent depression: A review of the past 10 years, part I. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 1427–1439.
Blankenship, K., Friedman, S., Dworkin, S., & Mantell, J. (2006). Structural interventions: Concepts, challenges and opportunities for research. Journal of Urban Health, 83(1), 59–72.
Brook, D. W., Brook, J. S., Zhang, C., Cohen, P., & Whiteman, M. (2002). Drug use and the risk of major depressive disorder, alcohol dependence, and substance use disorders. Archives of General Psychiatry, 59, 1039–1044.
Brook, J. S., Cohen, P., & Brook, D. W. (1998). Longitudinal study of co-occurring psychiatric disorders and substance use. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 322–330.
Brooks-Gunn, J., & Paikoff, R. (1997). Sexuality and developmental transitions during adolescence. In J. Schulenberg, J. Maggs, & K. Hurrelmann (Eds.), Health risks and developmental transactions during adolescence (pp. 190–219). New York, NY: Cambridge University Press.
Brown, L. K., Danovsky, M. B., Lourie, K. J., DiClemente, R. J., Ralph, J., & Ponton, L. E. (1997). Adolescents with psychiatric disorders and the risk of HIV. Journal of the American Academy of Child and Adolescent Psychiatry, 36(11), 1609–1617.
Brown, L. K., Tolou-Shams, M., Lescano, C., Houck, C., Zeidman, J., Pugatch, D., et al. (2006). Depressive symptoms as a predictor of sexual risk among African American adolescents and young adults. Journal of Adolescent Health, 39(3), 444.e1–444.e8.
Centers for Disease Control and Prevention. (2008a). Sexually transmitted disease surveillance 2007. Retrieved July 20, 2009, from http://www.cdc.gov/std/stats07/toc.htm.
Centers for Disease Control and Prevention. (2008b). Youth risk surveillance—United States 2007. MMWR, 57(SS-4). Retrieved July 9, 2009, from http://www.cdc.gov/HealthyYouth/yrbs/pdf/yrbss07_mmwr.pdf.
Centers for Disease Control and Prevention. (2008c). HIV/AIDS among youth. Retrieved August 26, 2009, from http://www.cdc.gov/hiv/resources/factsheets/youth.htm.
Chen, Y., Stiffman, A. R., Cheng, L., & Dore, P. (1997). Mental health, social environment and sexual risk behaviors of adolescent service users: A gender comparison. Journal of Child and Family Studies, 6(1), 9–25.
Collins, R. L., Ellickson, P. L., Orlando, M., & Klein, D. J. (2005). Isolating the nexus of substance use, violence and sexual risk for HIV infection among young adults in the United States. AIDS and Behavior, 9(1), 73–87.
Cook, R. L., Comer, D. M., Wisenfeld, H. C., Chang, C., Tarter, R., Lave, J. R., et al. (2006). Alcohol and drug use and related disorders: An underrecognized health issue among adolescents and young adults attending sexually transmitted disease clinics. Sexually Transmitted Diseases, 33(9), 565–570.
Dausey, D. J., & Desai, R. A. (2003). Psychiatric comorbidity and the prevalence of HIV infection in a sample of patients in treatment for substance abuse. The Journal of Nervous and Mental Disease, 191(1), 10–17.
Dermen, K. H., Cooper, M. L., & Agocha, V. B. (1998). Sex-related alcohol expectancies as moderators of the relationship between alcohol use and risky sex in adolescents. Journal of Studies on Alcohol, 59(1), 71–77.
Derogatis, L. R., & Spencer, P. M. (1982). The Brief Symptom Inventory (BSI): Administration and procedures. Manual-I. Baltimore, MD: Clinical Psychometric Research.
Deykin, E. Y., Levy, J. C., & Wells, V. (1987). Adolescent depression, alcohol and drug abuse. American Journal of Public Health, 77(2), 178–182.
Doljanac, R. F., & Zimmerman, M. A. (1998). Psychosocial factors and high risk sexual behavior: Race differences among urban adolescents. Journal of Behavioral Medicine, 21, 451–467.
Donenberg, G. R., Emerson, E., Bryant, F. B., Wilson, H., & Weber-Shifrin, E. (2001). Understanding AIDS-risk behavior among adolescents in psychiatric care: Links to psychopathology and peer relationships. Journal of the American Academy of Child Adolescent Psychiatry, 40(6), 642–653.
Donenberg, G. R., & Pao, M. (2005). Youths and HIV/AIDS: Psychiatry’s role in a changing epidemic. Journal of the American Academy of Child Adolescent Psychiatry, 44(8), 728–747.
Dworkin, S., Pinto, R. M., Hunter, J., Rapkin, B., & Remien, R. (2008). Keeping the spirit of community partnerships alive in the scale up of HIV/AIDS prevention: Critical reflections on the roll-out of DEBI (diffusion of effective behavioral interventions). American Journal of Community Psychology, 42(1–2), 51–59.
Elkington, K. S., Bauermeister, J. A., Brackis-Cott, E., Dolezal, C., & Mellins, C. A. (2009). Substance use and sexual risk behaviors in perinatally human immunodeficiency virus-exposed youth: The role of caregivers, peers and HIV status. Journal of Adolescent Health, 45(2), 133–141.
Elkington, K. S., Teplin, L. A., Mericle, A. A., Welty, L. J., Romero, E. G., & Abram, K. M. (2008). HIV/STI risk behaviors in delinquent youth with psychiatric disorders: A longitudinal study. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 901–911.
Ellickson, P. L., McCaffrey, D. F., & Klein, D. J. (2009). Long-term effects of drug prevention of risky sexual behavior among young adults. Journal of Adolescent Health, 45, 111–117.
Fergus, S., & Zimmerman, M. A. (2005). Adolescent resilience: A framework for understanding healthy development in the face of risk. Annual Review of Public Health, 26, 399–419.
Gordon, C. M., Carey, M. P., & Carey, K. B. (1997). Effects of a drinking event on behavioral skills and condom attitudes in men: Implications for HIV risk from a controlled experiment. Health Psychology, 16, 490–495.
Graves, K. L., & Leigh, B. C. (1995). The relationship of substance use to sexual activity among young adults in the United States. Family Planning Perspectives, 27(1), 18–22.
Greene, J. M., Ennett, S. T., & Ringwalt, C. L. (1999). Prevalence and correlates of survival sex among runaway and homeless youth. American Journal of Public Health, 89(9), 1406–1409.
Guo, J., Chung, I. J., Hill, K. G., Hawkins, J. D., Catalano, R. F., & Abbott, R. D. (2002). Developmental relationships between adolescent substance use and risky sexual behavior in young adulthood. Journal of Adolescent Health, 31(4), 354–362.
Hamilton, E. B., Asarnow, J. R., & Tompson, M. C. (1999). Family interaction styles of children with depressive disorders, schizophrenia-spectrum disorders, and normal controls. Family Process, 38(4), 463–476.
Houck, C. D., Lescano, C. M., Brown, L. K., Tolou-Shams, M., Thompson, J., DiClemente, R., et al. (2006). “Islands of risk”: Subgroups of adolescents at risk for HIV. Journal of Pediatric Psychology, 31(6), 619–629.
Kandel, D. B., Johnson, J. G., Bird, H. R., Canino, G., Goodman, S. H., Lahey, B. B., et al. (1997). Psychiatric disorders associated with substance use among children and adolescents: Findings from the methods for the epidemiology of child and adolescent mental disorders (MECA) study. Journal of Abnormal Child Psychiatry, 25(2), 121–132.
Kandel, D. B., Yamaguchi, K., & Chen, K. (1992). Stages of progression in drug involvement from adolescence to adulthood: Further evidence for the gateway theory. Journal of Studies on Alcohol, 53(5), 447–457.
Kelder, S. H., Murray, N. G., Orpinas, P., Prokhorov, A., McReynolds, L., Zhang, Q., et al. (2001). Depression and substance use in minority middle-school students. American Journal of Public Health, 91(5), 761–766.
Kessler, R., Avenevoli, S., & Merikangas, K. (2001). Mood disorders in children and adolescents: An epidemiologic perspective. Biological Psychiatry, 49(12), 1002–1014.
Kessler, R. C. (2004). The epidemiology of dual diagnosis. Biological Psychiatry, 56(10), 730–737.
Krull, J. L., & MacKinnon, D. P. (1999). Multilevel mediation modeling in group-based intervention studies. Evaluation Review, 23(4), 418–444.
LaBrie, J., Earlywine, M., Schiffman, J., Pedersen, E., & Marriot, C. (2005). Effects of alcohol, expectancies, and partner type on condom use in college males: Event-level analyses. Journal of Sex Research, 42, 259–266.
Lehrer, J. A., Shrier, L. A., Gortmaker, S., & Buka, S. (2006). Depressive symptoms as a longitudinal predictor of sexual risk behaviors among US middle and high school students. Pediatrics, 118(1), 189–200.
Lewinsohn, P. M., Gotlib, I. H., & Seeley, J. R. (1995). Adolescent psychopathology, IV: Specificity of psychosocial risk factors for depression and substance abuse in older adolescents. Journal of the American Academy of Child Adolescent Psychiatry, 34(9), 1221–1229.
Logan, T. K., Cole, J., & Leukefeld, C. (2002). Women, sex, and HIV: Social and contextual factors, meta-analysis of published interventions, and implications for practice and research. Psychological Bulletin, 128(6), 851–885.
MacKinnon, D. P., Warsi, G., & Dwyer, J. H. (1995a). A simulation study of mediated effect measures. Multivariate Behavioral Research, 30, 41–62.
MacKinnon, D. P., Warsi, G., & Dwyer, J. H. (1995b). A simulation study of mediated effect measures: Erratum. Multivariate Behavioral Research, 30(3), ii.
Marston, C., & King, E. (2006). Factors that shape young people’s sexual behavior: A systematic review. Lancet, 368, 1581–1586.
McFarlane, A. H., Bellissimo, A., & Norman, G. R. (1995). The role of family and peers in social efficacy: Links to depression in adolescence. American Journal of Orthopsychiatry, 63, 402–410.
McKinnon, K. (1996). Sexual and drug-use risk behavior. In F. Cournos & N. Bakalar (Eds.), AIDS and people with severe mental illness: A handbook for mental health professionals (pp. 17–46). New Haven, CT: Yale University Press.
Mellins, C. A., Elkington, K. S., Bauermeister, J. A., Brackis-Cott, E., Dolezal, C., McKay, M., et al. (2009). Sexual and drug use behavior in perinatally-HIV-infected youth: Mental health and family influences. Journal of the American Academy of Child and Adolescent Psychiatry, 48(8), 810–819.
Nakao, K., & Treas, J. (1994). Updating occupational prestige and socioeconomic scores: How the new measures measure up. Sociological Methodology, 24, 1–72.
O’Hare, T. (2005). Risky sex and drinking contexts in freshman first offenders. Addictive Behaviors, 30(3), 585–588.
Oshri, A., Tubman, J. G., Wagner, E. F., Leon-Morris, S., & Snyders, J. (2008). Psychiatric symptom patterns, proximal risk factors, and sexual risk behaviors among youth in outpatient substance abuse treatment. American Journal of Orthopsychiatry, 78(4), 430–441.
Ott, M., Millstein, S., & Halpern-Felsher, B. (2004). Positive motivations for sex among male and female teens. Paper presented at the Annual Meeting of the Society for Adolescent Medicine, St. Louis, MO.
Pine, D., Cohen, E., Cohen, P., & Brook, J. (1999). Adolescent depressive symptoms as predictors of adult depression: Moodiness or mood disorder? American Journal of Psychiatry, 156, 133–135.
Ramirez-Valles, J., Zimmerman, M. A., & Newcomb, M. D. (1998). Sexual risk behavior among youth: Modeling the influence of prosocial activities and socioeconomic factors. Journal of Health and Social Behavior, 39, 237–253.
Ramrakha, S., Caspi, A., Dickson, N., Moffitt, T. E., & Paul, C. (2000). Psychiatric disorders and risky sexual behaviour in young adulthood: Cross sectional study in birth cohort. British Medical Journal, 321, 263–266.
Raudenbush, S., & Bryk, A. (2002). Hierarchical linear models: Applications and data analysis methods (2nd ed.). Thousand Oaks, CA: Sage.
Rogers, J. L. (1996). Sexual transitions in adolescence. In J. A. Graber, J. Brooks-Gunn, & A. C. Peterson (Eds.), Transitions through adolescence: Interpersonal domains and context (pp. 85–110). Mahwah, NJ: Erlbaum.
Rosenthal, D., Moore, S., & Flynn, I. (1991). Adolescent self-efficacy, self-esteem, and sexual risk-taking. Journal of Community and Applied Social Psychology, 1(2), 77–88.
Rubin, A. G., Gold, D. O., & Primack, B. A. (in press). Associations between depressive symptoms and sexual risk behavior in a diverse sample of female adolescents. Journal of Pediatric and Adolescent Gynocology.
Salazar, L. F., DiClemente, R. J., Wingood, G. M., Crosby, R. A., Harrington, K., Davies, S., et al. (2004). Self-concept and adolescents’ refusal of unprotected sex: A test of mediating mechanisms among African American girls. Prevention Science, 5(3), 137–149.
Sanderson, C., & Cantor, N. (1995). Social dating goals in late adolescence: Implications for safer sexual activity. Journal of Personality and Social Psychology, 68, 1121–1134.
Scientific Software International. (2009). Hierarchical linear models. Chicago, IL: SSI Inc.
Seal, A., Minichiello, V., & Omodei, M. (1997). Young women’s sexual risk taking behaviour: Revisiting the influences of sexual self-efficacy and sexual self-esteem. International Journal of STD and AIDS, 8, 159–165.
Shrier, L. A., Harris, S. K., Sternberg, M., & Beardslee, W. R. (2001). Associations of depression, self-esteem, and substance use with sexual risk among adolescents. Preventative Medicine, 33(3), 179–189.
Shrier, L., Harris, S., & Beardslee, W. (2002). Temporal associations between depressive symptoms and self-reported sexually transmitted disease among adolescents. Archives of Pediatric and Adolescent Medicine, 156(6), 599–606.
Smith, M. D. (2001). HIV risk in adolescents with severe mental illness: Literature review. Journal of Adolescent Health, 29, 320–329.
Stiffman, A. R., Dore, P., Earls, F., & Cunningham, R. (1992). The influence of mental health problems on AIDS-related risk behaviors in young adults. Journal of Nervous and Mental Disease, 180(5), 314–320.
Stoner, S. A., George, W. H., Peters, L. M., & Norris, J. (2007). Liquid courage: Alcohol fosters risky sexual decision-making in individuals with sexual fears. AIDS and Behavior, 11, 227–237.
Tapert, S. F., Aarons, G. A., Sedlar, G. R., & Brown, S. A. (2001). Adolescent substance use and sexual risk-taking behavior. Journal of Adolescent Health, 28(3), 181–189.
Teplin, L. A., Elkington, K. S., McClelland, G. M., Abram, K. M., Mericle, A. A., & Washburn, J. J. (2005). Major mental disorders, substance use disorders, comorbidity, and HIV-AIDS risk behaviors in juvenile detainees. Psychiatric Services, 56, 823–828.
Tolou-Shams, M., Brown, L. K., Houck, C., & Lescano, C. M. (2008). The association between depressive symptoms, substance use, and HIV risk among youth with an arrest history. Journal of Studies on Alcohol and Drugs, 69(1), 58–64.
Tolou-Shams, M., Paikoff, R. L., McKirnan, D. J., & Holmbeck, G. N. (2007). Mental health and HIV risk among African American adolescents: The role of parenting. Social Work in Mental Health, 5(1–2), 27–58.
Tubman, J., Windle, M., & Windle, R. (1996). The onset and cross-temporal patterning of sexual intercourse in middle adolescence: Prospective relations with behavioral and emotional problems. Child Development, 67(2), 327–343.
Acknowledgments
This work was supported by two National Institute of Drug Abuse grants (5R01DA007484-11; “A longitudinal study of school dropout and substance use”, and 1R03AA017240-01; “Protective factors for alcohol use among urban adolescents”) awarded to Dr. Zimmerman. Dr. Elkington is supported by the Center Grant P30 MH43520 to the HIV Center for Clinical and Behavioral Studies, Anke A. Ehrhardt, PhD, Principal Investigator, from the National Institute of Mental Health. All authors have nothing to disclose.
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Elkington, K.S., Bauermeister, J.A. & Zimmerman, M.A. Psychological Distress, Substance Use, and HIV/STI Risk Behaviors Among Youth. J Youth Adolescence 39, 514–527 (2010). https://doi.org/10.1007/s10964-010-9524-7
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DOI: https://doi.org/10.1007/s10964-010-9524-7