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Community-Responsive Interventions to Reduce Cardiovascular Risk in American Indians

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Abstract

American Indian and Alaska Native (AI/AN) populations bear a heavy burden of cardiovascular disease (CVD), and they have the highest rates of risk factors for CVD, such as cigarette smoking, obesity, and diabetes, of any U.S. population group. Yet, few randomized controlled trials have been launched to test potential preventive interventions in Indian Country. Five randomized controlled trials were initiated recently in AI/AN communities to test the effectiveness of interventions targeting adults and/or children to promote healthy behaviors that are known to impact biological CVD risk factors. This article provides a context for and an overview of these five trials. The high burden of CVD among AI/AN populations will worsen unless behaviors and lifestyles affecting CVD risk can be modified. These five trials, if successful, represent a starting point in addressing these significant health disparities.

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Acknowledgments

These trials were supported by 5 cooperative agreements between the funding agency and the institutions of the principal investigators. The authors thank the community partners who collaborated in these trials.

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Author notes

  1. Jared B. Jobe

    Present address: Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA

Authors and Affiliations

  1. Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD, USA

    Jared B. Jobe

  2. Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

    Alexandra K. Adams

  3. Black Hills Center for American Indian Health, Rapid City, SD, USA

    Jeffrey A. Henderson

  4. Center for Health Research, Kaiser Permanente, Northwest/Hawaii/Southeast, Portland, OR, USA

    Njeri Karanja

  5. Center for American Indian Health Research, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

    Elisa T. Lee

  6. University of Washington Indigenous Wellness Research Institute and School of Social Work, Seattle, WA, USA

    Karina L. Walters

Authors
  1. Jared B. Jobe
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  2. Alexandra K. Adams
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  3. Jeffrey A. Henderson
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  4. Njeri Karanja
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  5. Elisa T. Lee
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  6. Karina L. Walters
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Correspondence to Jared B. Jobe.

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Jobe, J.B., Adams, A.K., Henderson, J.A. et al. Community-Responsive Interventions to Reduce Cardiovascular Risk in American Indians. J Primary Prevent 33, 153–159 (2012). https://doi.org/10.1007/s10935-012-0277-9

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  • DOI: https://doi.org/10.1007/s10935-012-0277-9

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