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Measures of Physical and Cognitive Function and Work Status Among Individuals with Multiple Sclerosis: A Review of the Literature

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Abstract

The purpose of this review was to critically evaluate the multiple sclerosis (MS) literature that has examined physical and cognitive function in relation to ability to work. Although numerous factors may be considered when determining work ability, physical and/or cognitive functional limitations associated with MS are presumably the primary determinants of work capacity. An exhaustive search of the literature produced 20 research articles that described 18 studies. Findings from these studies support that limitations in physical or cognitive function can hinder one’s ability to work; however, ability to work could not be based solely on these measures of function. Work ability among individuals extended beyond measures of impairment to include level of education, job characteristics, and disease symptoms such as fatigue. In summary, measures of physical and cognitive function can guide physicians when clinically evaluating an individual with MS, but are poor indicators for precluding an individual from working.

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References

  • National Multiple Sclerosis Society. About MS. Retrieved February 04, 2004, from http:www. nationalmssociety. org/about.

  • Social Security Administration Office of Disability. Disability evaluation under social security January 2003 (SSA Pub. No. 64-039). Baltimore, MD: Social Security Administration Office of Disability, 2003.

  • Larocca N. Employment and multiple sclerosis. New York: National Multiple Sclerosis Society, 1995.

    Google Scholar 

  • Larocca N, Kalb R, Scheinberg L, Kendall P. Factors associated with unemployment of patients with multiple sclerosis. Journal of Chronic Disabilities 1985; 38: 203–210.

    Google Scholar 

  • Rumrill P, Roessler R. New directions in rehabilitation counseling: A career development perspective on closure. Journal of Rehabilitation 1999; 65(1): 26–30.

    Google Scholar 

  • Rumrill P. Employment issues and multiple sclerosis. New York: Demos, 1996.

    Google Scholar 

  • Beatty WW, Blanco CR, Wilbanks SL, Demographic, clinical and cognitive characteristics of multiple sclerosis patients who continue to work. J Neurol Rehab 1995; 9: 167–173.

    Google Scholar 

  • Backman CL, Kennedy SM, Chalmers A, Singer J. Participation in paid and unpaid work by adults with rheumatoid arthritis. J Rheumatol 2004; 31: 47–56.

    Google Scholar 

  • Chorus AM, Miedema HS, Boonen A, Van Der Linden S. Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age. Ann Rheum Dis 2003; 62: 1178–1184.

    Google Scholar 

  • Hirth RA, Chernew ME, Turenne MN. Chronic illness, treatment choice and workforce participation. Inter J Health Care Finance Econ 2003; 3: 167–181.

    Google Scholar 

  • Wingate S, Loscalzo F, Hozdic T. Perceptions of activity and vocational status in women with cardiac illness. Prog Cardiovasc Nurse 2003; 18: 127–133, 146.

    Google Scholar 

  • Kessler RC, Greenberg PE, Mickelson KD, Meneades LM, Wang PS. The effects of chronic medical conditions on work loss and work cutback. J Occup Environ Med 2001; 43: 218–225.

    Google Scholar 

  • Taylor JC, Terrell JE, Ronis DL, Fowler KE, Bishop C, Lambert MT, Disability in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 2004; 130(6): 764–769.

    Google Scholar 

  • Bradley CJ, Bednarek HL, Neumark D. Breast cancer and women’s labor supply. Health Serv Res 2002; 37(5): 1309–1328.

    Google Scholar 

  • Canadian Burden of Illness Study Group. Burden of illness of multiple sclerosis. Part I: Cost of illness. Can J Neurol Sci 1998; 25(1): 23–30.

    Google Scholar 

  • Canadian Burden of Illness Study Group. Burden of illness of multiple sclerosis. Part II: Quality of life. Can J Neurol Sci 1998; 25(1): 31–38.

    Google Scholar 

  • Edgley K, Sullivan M, Dehoux E. A survey of multiple sclerosis: Determinants of employment status. Can J Rehabil 1991; 4: 127–132.

    Google Scholar 

  • Freal JE, Kraft GH, Coryell JK. Symptomatic fatigue in multiple sclerosis. Arch Phys Med Rehabil 1984; 65(3): 135–138.

    Google Scholar 

  • Genevie L, Kallos JE, Struening EL. Job retention among people with multiple sclerosis. J Neurol Rehabil 1987; 1: 131–135.

    Google Scholar 

  • Grima DT, Torrance GW, Francis G, Cost and health related quality of life consequences of multiple sclerosis. Mult Scler 2000; 6(2): 91–98.

    Google Scholar 

  • Gulick EE, Yam M, Touw MM. Work performance by persons with multiple sclerosis: Conditions that impede or enable the performance of work. Intern J Nurs Stud 1989; 26(4): 301–311.

    Google Scholar 

  • Hammond SR, McLeod JG, Macaskill P, Multiple sclerosis in Australia: socioeconomic factors. J Neurol Neurosurg Psych 1996; 61(3): 311–313.

    Google Scholar 

  • Jacobs LD, Wende KE, Brownscheidle CM, A profile of multiple sclerosis: The New York State Multiple Sclerosis Consortium. Mult Scler 1999; 5(5): 369–376.

    Google Scholar 

  • Jongbloed L. Factors influencing employment status of women with multiple sclerosis. Can J Rehabil 1996; 9: 213–222.

    Google Scholar 

  • Dyck I, Jongbloed L. Women with multiple sclerosis and employment issues: A focus on social and institutional environments. Can J Occup Therapy 2000; 67(5): 337–346.

    Google Scholar 

  • Kornblith AB, La Rocca NG, Baum HM. Employment in individuals with multiple sclerosis. Intern J Rehabil Res 1986; 9(2): 155–165.

    Google Scholar 

  • LaRocca N, Kalb R, Kendall P, The role of disease and demographic factors in the employment of patients with multiple sclerosis. Arch Neurol 1982; 39(4): 256.

    Google Scholar 

  • Miller DM, Rudick RA, Cutter G, Clinical significance of the multiple sclerosis functional composite: Relationship to patient-reported quality of life. Arch Neurol 2000; 57(9): 1319–1324.

    Article  CAS  PubMed  Google Scholar 

  • Rao SM, Leo GJ, Ellington L, Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning. Neurology 1991; 41(5): 692–696.

    CAS  PubMed  Google Scholar 

  • Rozin R, Schiff Y, Cooper G, Vocational rehabilitation of multiple sclerosis (MS) patients. I. Analysis of clinical and demographic factors. Intern Rehabil Med 1982; 4(2): 75–79.

    Google Scholar 

  • Rozin R, Schiff Y, Kahana E, Vocational status of multiple sclerosis patients in Israel. Arch Phys Med Rehabil 1975; 56(7): 300–304.

    Google Scholar 

  • Scheinberg L, Holland N, Larocca N, Multiple sclerosis; earning a living. NY State J Med 1980; 80(9): 1395–1400.

    Google Scholar 

  • Verdier-Taillefer MH, Sazdovitch V, Borgel F, Occupational environment as risk factor for unemployment in multiple sclerosis. Acta Neurol Scand 1995; 92(1): 59–62.

    Google Scholar 

  • Beukelman DR, Kraft GH, Freal J. Expressive communication disorders in persons with multiple sclerosis: A survey. Arch Phys Med Rehabil 1985; 66(10): 675–677.

    Google Scholar 

  • Grønning M, Hannisdal E, Mellgren SI. Multivariate analyses of factors associated with unemployment in people with multiple sclerosis. J Neurol Neurosurg Psychiatry 1990; 53(5): 388–390.

    Google Scholar 

  • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 1983; 33(11): 1444–1452.

    CAS  PubMed  Google Scholar 

  • Richards RG, Sampson FC, Beard SM, A review of the natural history and epidemiology of multiple sclerosis: Implications for resource allocation and health economic models [review]. Health Technol Assess (Winchester, England) 2002; 6(10): 1–73.

    Google Scholar 

  • Arnold DL, Bouchard JP, Boyle CAJ, Key issues in the diagnosis and treatment of multiple sclerosis-an overview. Neurology 2002; 59(6): U2–S33.

    Google Scholar 

  • Hale TW, Hayghe HV, McNeil JM. Persons with disabilities: Labor market activity, 1994. Monthly Lab Rev 1998; Sept: 3–12.

    Google Scholar 

  • Smith K, Downs B, O;Connell M. Maternity leave and employment patterns: 1961–1995. Current Population Reports, U.S. Census Bureau, Washington, DC, 2001, pp 70–79.

    Google Scholar 

  • Cohen PN, Bianchi SM. Marriage, children, and women’s employment: What do we know? Monthly Labor Rev 1999; Dec: 22–31.

    Google Scholar 

  • Joy JE, Johnston RB. Multiple sclerosis: Current status and strategies for the future, Washington, DC: National Academy Press, 2003.

    Google Scholar 

  • Krueger R, Casey MA. Focus groups: A practical guide for applied research, 3rd edn. London: Sage, 2000.

    Google Scholar 

  • Wald NJ, Hackshaw AK, Frost CD. When can a risk factor be used as a worthwhile screening test? [Review]. BMJ 1999; 319(7224): 1562–1565.

    Google Scholar 

  • Rockhill B, Byrne C, Rosner B, Breast cancer risk prediction with a log-incidence model: Evaluation of accuracy. J Clin Epidemiol 2003; 56(9): 856–861.

    Google Scholar 

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Pompeii, L.A., Moon, S.D. & McCrory, D.C. Measures of Physical and Cognitive Function and Work Status Among Individuals with Multiple Sclerosis: A Review of the Literature. J Occup Rehabil 15, 69–84 (2005). https://doi.org/10.1007/s10926-005-0875-y

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