Abstract
In order to investigate the relationship between changes in blood circulation and bone mineral density (BMD) loss, the characteristic parameters reflecting the function of tissue oxygen metabolism are obtained by means of blood oxygen level-dependent magnetic resonance imaging (BOLD-MRI), image processing and semi-quantitative analysis. The correlation and variance analysis of the characteristic parameters of different BMD groups are carried out, and the physiological parameters of bone marrow blood perfusion are obtained by dynamic enhanced MRI (DCE-MRI). Multivariate logistic regression analysis is carried out with the physiological parameters of blood oxygen metabolism function and bone marrow blood perfusion as independent variables and BMD as dependent variables. It is found that there are significant differences in oxygen metabolism between individual muscles in different BMD groups and between skeletal muscles of different types of muscle fibers. Age, total volume of bone marrow and oxygen metabolism ability of tibial anterior muscle have significant independent effects on osteoporosis. It shows that the changes of blood circulation in bone marrow and surrounding muscle tissue are indeed one of the causes of osteoporosis.
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Author Xiaoming Qiu declares that he has no conflict of interest. Author Yufei Fu declares that he has no conflict of interest. Author Jiao Chen declares that he has no conflict of interest. Author Yu Ye declares that he has no conflict of interest. Author Zhen Wang declares that he has no conflict of interest. Author Xianfang Ming declares that he has no conflict of interest.
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Qiu, X., Fu, Y., Chen, J. et al. The Correlation between Osteoporosis and Blood Circulation Function Based on Magnetic Resonance Imaging. J Med Syst 43, 91 (2019). https://doi.org/10.1007/s10916-019-1206-8
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DOI: https://doi.org/10.1007/s10916-019-1206-8