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In-Vitro Antibacterial, Antioxidant and Cytotoxic Potential of Silver Nanoparticles Synthesized Using Novel Eucalyptus tereticornis Leaves Extract

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Abstract

In present study, silver nanoparticles (AgNPs) were synthesized using Eucalyptus tereticornis leaves extract as bioreducing agent. Prepared AgNPs were characterized and confirmed using various analytical tools such as UV–Vis spectroscopy, XRD, SEM with EDS and TEM. Crystallographic studies were carried by XRD analysis. Size, morphology was studied by SEM, TEM and elemental composition confirmed by EDS respectively. AgNPs showed significant antibacterial activity against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacterial strains. AgNPs also exhibited promising 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with IC50 59.0 μg/mL. Further, cytotoxic activity performed on Michigan Cancer Foundation-7 (MCF-7) cell line proved that the prepared AgNPs have potential anticancer activity having 63.257 μg/ml 50% inhibition concentration.

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Authors and Affiliations

  1. Research Centre, Department of Chemistry, GM Institute of Technology, Davangere, Karnataka, 577006, India

    M. S. Kiran, Virupaxappa S. Betageri, C. R. Rajith Kumar & M. S. Latha

  2. Research and Development Centre, Department of Chemistry, Shridevi Institute of Engineering and Technology, Tumakuru, Karnataka, 572106, India

    S. P. Vinay

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  1. M. S. Kiran
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  2. Virupaxappa S. Betageri
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Kiran, M.S., Betageri, V.S., Kumar, C.R.R. et al. In-Vitro Antibacterial, Antioxidant and Cytotoxic Potential of Silver Nanoparticles Synthesized Using Novel Eucalyptus tereticornis Leaves Extract. J Inorg Organomet Polym 30, 2916–2925 (2020). https://doi.org/10.1007/s10904-020-01443-7

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