Abstract
Zinc containing oil based polyesteramide resins were synthesized by condensation polymerization reaction between castor/soyabean oil derived castor/soyabean fatty amide diol (HECA/HESA), Zn (OH)2 and adipic acid. The conventional spectroscopic techniques such as FTIR, 1HNMR, 13CNMR have been used to establish the structure of the polymers. Standard laboratory methods were used to study the physicochemical characteristics like acid value, hydroxyl value, saponification value, iodine value, specific gravity, and viscosity. The thermal behaviour of the polymers was analyzed by using thermo gravimetric analysis (TGA) and differential scanning calorimetry (DSC). In vitro antifungal (anticandidial) activity of the polymers was studied against C. albicans ATCC-10261, C. glabrata ATCC-90030 and C. tropicalis ATCC-750, respectively. Antibacterial activity against Gram positive (S. subtillis) and Gram negative bacteria (E. coli and S. typhi) was also examined. For more accuracy, growth curve studies were carried out with the polymer SZ showing higher biological activity against E. coli by using conventional spectrophotometer. The result showed that the polymers have potent anticandidial and antibacterial activities.
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Bharathi, N.P., Khan, N.U., Shreaz, S. et al. Seed Oil Based Zinc Bioactive Polymers: Synthesis, Characterization and Biological Studies. J Inorg Organomet Polym 19, 558–565 (2009). https://doi.org/10.1007/s10904-009-9299-z
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DOI: https://doi.org/10.1007/s10904-009-9299-z