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Association Between the Hypertriglyceridemic Waist Phenotype, Prediabetes, and Diabetes Mellitus Among Adults in Puerto Rico

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Abstract

This study assessed the association of the hypertriglyceridemic waist (HTGW) phenotype with prediabetes and diabetes (DM) in a group of Hispanics. Analysis of a cross-sectional study of 858 adults residing in Puerto Rico that collected data on blood pressure, biochemical, and anthropometric measurements was performed. HTGW phenotype was defined as elevated triglycerides and elevated waist circumference. Prediabetes was defined as a fasting glucose of 100–125 mg/dL and DM as a fasting glucose ≥126 mg/dL or prior diagnosis. Prevalence of HTGW, prediabetes, and DM was 27.9, 38.0, and 21.6 %, respectively. Subjects with the HTGW phenotype had higher adjusted odds of prediabetes (POR 5.55; 95 % CI 3.38–9.13) and DM (POR 7.28; 95 % CI 3.63–14.63) compared to those without the phenotype. The association for prediabetes was stronger for women than among men. HTGW phenotype was strongly associated with prediabetes and DM, reinforcing the need to further assess its performance as a screening tool to identify at-risk individuals for cardiometabolic conditions.

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Acknowledgments

The project described was supported by an unrestricted grant from Merck Sharp & Dohme Corporation with additional support from the National Institute on Minority Health and Health Disparities (U54 MD 007587-03) from the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official view of Merck Sharp & Dohme Corporation or the National Institutes of Health. The authors wish to acknowledge Dr. Katherine Reeves (University of Massachusetts, School of Public Health, Amherst, Massachusetts) for her helpful suggestions on the manuscript.

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Authors and Affiliations

  1. Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA

    Mary Vanellys Díaz-Santana, Erick L. Suárez Pérez, Ana P. Ortiz Martínez & Cynthia M. Pérez Cardona

  2. School of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA

    Manuel Guzmán Serrano

  3. Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, 408 Arnold House, 715N. Pleasant Street, Amherst, MA, 01003-9304, USA

    Mary Vanellys Díaz-Santana

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  1. Mary Vanellys Díaz-Santana
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Correspondence to Mary Vanellys Díaz-Santana.

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Díaz-Santana, M.V., Suárez Pérez, E.L., Ortiz Martínez, A.P. et al. Association Between the Hypertriglyceridemic Waist Phenotype, Prediabetes, and Diabetes Mellitus Among Adults in Puerto Rico. J Immigrant Minority Health 18, 102–109 (2016). https://doi.org/10.1007/s10903-014-9985-y

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