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Comparing Health-Related Quality of Life among Breast Cancer Patients Receiving Different Plans of Treatment, Egypt

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Abstract

The increased survival of breast cancer (BC) patients by earlier detection and improved treatment outcomes together with younger age at diagnosis, raised the concerns about Quality Of Life among survivors, suffering from treatment side effects. To measure QOL among BC Egyptian females, then to compare HRQOL scores in BC patients receiving different lines of treatment. A comparative cross-sectional study on a sample 142 BC survivor receiving different lines of treatment, using EORTC QLQ-C30, and a BC-specific scale (QLQBR23 scale). The emotional functioning had the lowest score (29.22 ± 8.1), the most prominent symptom was appetite loss (69.48 ± 15.6) and in QLQ-BC23 scale, the future perspectives had the lowest score among functioning scale (19.71 ± 4.9). While among the symptoms scale; the most annoying symptom was upset by hair loss (89.67 ± 15.5). A significant difference in emotional subscale between three lines of treatment (p = 0.000) with the hormone therapy had the highest Global QOL (41.17 ± 9.97) (p = 0.008). Significant inverse correlation between the level of Global QOL and presence of chronic disease in the chemotherapy group (p = 0.001) and stage of carcinoma in all lines of treatment. Moreover the results proved that age and stage of carcinoma were the significant predictors for Global QOL. Hormonal therapy group showed the best functional scale in all subdomains of QLQ-C30 and QLQ-BC23, while radiotherapy group showed the lowest scores in QOL-C30 and chemotherapy group in QLQ-BC23. Chemotherapy group shows the highest level of problematic Global QOL with appetite loss in QLQ-C30 and upset from hair loss in QLQ-BC23.

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Acknowledgements

We would like to express appreciation to both all patients who agree to participate.

Funding

Totally paid by researchers.

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Authors and Affiliations

  1. Community, Environmental and Occupational Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

    Eman M. Mortada & Omnia S. Elseifi

  2. Health Sciences Department, Health And Rehabilitation Sciences College, Princess Nourha Bent Abdulrahman University, Riyadh, Saudi Arabia

    Eman M. Mortada

  3. Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

    Reham A. Salem

  4. Radiological Sciences Department, Health And Rehabilitation Sciences College, Princess Noura Bint Abdulrahman University, Riyadh, Saudi Arabia

    Reham A. Salem

  5. General Surgery Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

    Osama M. Khalil

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  1. Eman M. Mortada
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Correspondence to Eman M. Mortada.

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“All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.”

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Mortada, E.M., Salem, R.A., Elseifi, O.S. et al. Comparing Health-Related Quality of Life among Breast Cancer Patients Receiving Different Plans of Treatment, Egypt. J Community Health 43, 1183–1191 (2018). https://doi.org/10.1007/s10900-018-0538-5

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  • DOI: https://doi.org/10.1007/s10900-018-0538-5

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