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Prenatal Genetic Testing: An Investigation of Determining Factors Affecting the Decision-Making Process

  • Original Research
  • Published:
Journal of Genetic Counseling

Abstract

Despite the increase in popularity of prenatal genetic testing, relatively little is known about the role psychological factors play in the decision-making process. In this analogue study, a sample of Italian female university students was used to investigate determining factors that predict the intention of undergoing prenatal genetic testing. Structural Equation Modelling was used to describe the dynamic interplay between knowledge, beliefs, attitudes and health-related behaviour such as prenatal genetic testing. Following the Theory of Reasoned Action, three dimensions predicted the intention to undergo prenatal genetic testing: the need for more scientific information, a positive attitude towards genetic testing, and the inclination to terminate pregnancy after receiving a positive test result. Results showed that less religious women tended to be more in favour of prenatal tests and in undertaking such tests. This preliminary study provides genetic counsellors and policy makers with a clearer picture of their clients’ motives and attitudes behind the decision-making process of prenatal genetic testing, contributing to improving both the communication process between counsellors and their clients and the organization of genetic services.

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Notes

  1. Covariance matrix was analyzed and Maximum Likelihood Method was used

  2. For the SEM, the sample included 132 participants since the list-wise deletion method was chosen for handling missing data.

References

  • A.I.P. (2000) Code of ethics of the Italian psychological association. Retrieved on-line on June 2011 from https://doi.org/www.aipass.org/node/26

  • Ahmed, S., Atkin, K., Hewison, J., & Green, J. (2006). The influence of faith and religion and the role of religious and community leaders in prenatal decisions for sickle cell disorders and thalassaemia major. Prenatal Diagnosis, 26, 801–809. doi:https://doi.org/10.1002/pd.1507.

    Article  PubMed  Google Scholar 

  • Ahmed, S., Green, J. M., & Hewison, J. (2006). Attitudes towards prenatal diagnosis and terminationof pregnancy for thalassaemia in pregnant Pakistani women in the North of England. Prenatal Diagnosis, 26, 248–257. doi:https://doi.org/10.1002/pd.1391.

    Article  PubMed  Google Scholar 

  • Ajzen, I. (1991). The theory of planned behaviour. Organizational Behaviour and Human Decision Processes, 50(2), 179–211.

    Article  Google Scholar 

  • Ajzen, I. (1988). Attitudes, personality, and behaviour. Milton-Keynes: Open University Press.

    Google Scholar 

  • Allum, N., Sturgis, P., Tabourazi, D., & Brunton-Smith, I. (2008). Science knowledge and attitudes across cultures: a meta-analysis. Public Understanding of Science, 17(1), 35–54.

    Article  Google Scholar 

  • Aro, A. R., Hakonen, A., Hietala, M., Lonnqvist, J., Niemelä, P., Peltonen, L., & Aula, P. (1997). Acceptance of genetic testing in a general population: age, education and gender differences. Patient Education and Counseling, 32, 41–49.

    Article  CAS  PubMed  Google Scholar 

  • Baron, R. M., & Kenny, D. A. (1986). The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173–1182.

    Article  CAS  PubMed  Google Scholar 

  • Bauer, M. W., Durant, J., & Evans, G. (1994). European public perceptions of science. International Journal of Public Opinion Research, 6(2), 163–186.

    Article  Google Scholar 

  • Bauer, M. W., Allum, N., & Miller, S. (2007). What can we learn from 25-years of PUS research? Liberating and expanding the agenda. Public Understanding of Science, 16(1), 79–95.

    Article  Google Scholar 

  • Boggio, A. (2005). Italy enacts new law on medically assisted reproduction. Human Reproduction, 20, 1153–1157.

    Article  PubMed  Google Scholar 

  • Braithwaite, D., Sutton, S., & Steggles, N. (2002). Intention to participate in predictive genetic testing for hereditary cancer: the role of attitude toward uncertainty. Psychology and Health, 17, 761–772.

    Article  Google Scholar 

  • Browner, C. H., & Preloran, H. M. (1999). Male partners’ role in Latinas’ amniocentesis decisions. Journal of Genetic Counseling, 8(2), 85–107.

    Article  PubMed  Google Scholar 

  • Browner, C. H., Preloran, H. M., Casado, M. C., Bass, H., & Walker, A. (2003). Genetic counselling gone awry: some consequences of miscommunication between prenatal genetic service providers and Latina clients. Social Science & Medicine, 56(9), 1933–1946.

    Article  CAS  Google Scholar 

  • Cappelli, M., Surh, L., Humphreys, L., Verma, S., Logan, D., Hunter, A., & Allanson, J. (2001). Psychological and social determinants of women’s decisions to undergo genetic counselling and testing for breast cancer. Clinical Genetics, 55(6), 419–430.

    Article  Google Scholar 

  • Caricati, L. (2007). Power of genetics: adaptation and validation of a scale for measuring Belief in Genetic Determinism (BGD) with classical test analysis and rasch analysis. TPM, 14(2), 99–112.

    Google Scholar 

  • Catz, D. S., Green, N. S., Tobin, J. N., Lloyd-Puryear, M. A., Kyler, P., Umemoto, A., Cernoch, J., Brown, R., & Wolman, F. (2005). Attitudes about genetics in underserved, culturally diverse populations. Community Genetics, 8(3), 161–172.

    PubMed  Google Scholar 

  • Cipriani, R., & Bove, G. (2003). Le multiple forme del pluralismo religioso [Multiple forms of religious pluralism]. In F. Garelli, G. Guizzardi, & E. Pace (Eds.), Un singolare pluralismo (pp. 159–191). Bologna: Il Mulino.

    Google Scholar 

  • Conferenza Stato-Regioni (2004). Linee guida per le attività di genetica medica [Guidelines to activities on medical genetics]. Retrieved on September 2008 from https://doi.org/www.statoregioni.it/Notizia.asp?IDKey=19.

  • Dei Tos, G. A. (2007). Etica e genetica. Studi Zancan, 2, 133–149.

    Google Scholar 

  • Dormandy, E., Hankins, M., & Marteau, T. (2006). Attitudes and uptake of a screening test: the moderating role of ambivalence. Psychological Health, 21(4), 499–511.

    Article  Google Scholar 

  • Dormandy, E., & Marteau, T. M. (2004). Uptake of a prenatal screening test: the role of healthcare professionals’ attitudes towards the test. Prenatal Diagnosis, 24, 864–868. doi:https://doi.org/10.1002/pd.1028.

    Article  PubMed  Google Scholar 

  • Durant, J., Bauer, M., Midden, C., Gaskell, G., & Liakopoulos, M. (2000). Two cultures of public understanding of science. In M. Dierkes & C. von Grote (Eds.), Between understanding and trust: The public, science and technology (pp. 131–156). Amsterdam: Harwood Academic Publishers.

    Google Scholar 

  • Durant, J. R., Evans, G. A., & Thomas, G. P. (1989). The public understanding of science. Nature, 340, 11–14.

    Article  CAS  PubMed  Google Scholar 

  • Edwards, J. (2002). Taking public understanding seriously. New Genetics and Society, 21(3), 315–325.

    Article  Google Scholar 

  • EORG (2006). Eurobarometer 64.3. Retrieved on September 2009 from https://doi.org/ec.europa.eu/research/press/2006/pdf/pr1906_eb_64_3_final_report-may2006_en.pdf

  • Etchegary, H. (2004). Psychological aspects of predictive genetic test decisions: what do we know so far? Analyses of Social Issues and Public Policy, 4, 13–31.

    Article  Google Scholar 

  • Fishbein, M., & Ajzen, I. (1975). Belief, attitude, intention, and behaviour: An introduction to theory and research. Reading: Addison-Wesley.

    Google Scholar 

  • Fraser, C. (1994). Attitudes, social representations and widespread beliefs. Papers on Social Representations, 3(1). Retrieved March 2002, from https://doi.org/www.psr.jku.at/psrindex.htm

  • Frost, S., Myers, L. B., & Newman, S. P. (2001). Genetic screening for Alzheimer’s disease: what factors predict intentions to take a test? Behavioural Medicine, 27, 101–109.

    Article  CAS  Google Scholar 

  • Furr, L. A., & Seger, R. E. (1998). Psychosocial predictors of interest in prenatal genetic screening. Psychiatry Reports, 82(1), 235–244.

    Article  CAS  Google Scholar 

  • G.U. n. 216, September 14th (1996). Decreto Ministeriale 22 luglio 1996. Prestazioni di assistenza specialistica ambulatoriale erogabili nell’ambito del Servizio sanitario nazionale e relative tariffe. Retrieved on August 2010 from https://doi.org/www.normativasanitaria.it/jsp/dettaglio.jsp?id=6403

  • Garcia, E., Timmermans, D. R., & van Leeuwen, E. (2008). Rethinking autonomy in the context of prenatal screening decision-making. Prenatal Diagnosis, 28, 115–120.

    Article  PubMed  Google Scholar 

  • Gaskell, G., Allum, N. C., Wagner, W., Hviid Nielsen, T., Jelsoe, E., Kohring, M., & Bauer, M. W. (2001). In the public eye: Representations of biotechnology in Europe. In G. Gaskell & M. Bauer (Eds.), Biotechnology 1996–2000: the years of controversy (pp. 53–79). London: Science Museum Publications.

    Google Scholar 

  • Gelfand, L. A., Mensinger, J. L., & Tenhave, T. (2009). Mediation analysis: a retrospective snapshot of practice and more recent directions. The Journal of General Psychology, 136(2), 153–176.

    Article  PubMed  PubMed Central  Google Scholar 

  • Glanz, K., Grove, J., Lerman, C., Gotay, C., & LeMarchand, L. (1999). Correlates of intentions to obtain genetic counseling and colorectal cancer genetic testing among at-risk relatives from three ethnic groups. Cancer Epidemiology, Biomarkers & Prevention, 8, 329–336.

    CAS  Google Scholar 

  • Glanz, K., Rimer, B. K., & Lewis, F. M. (2002). Health behavior and health education. Theory, research and practice. San Francisco: Wiley.

    Google Scholar 

  • Halbert, C. H., Kessler, L. J., & Mitchell, E. (2005). Genetic testing for inherited breast cancer in African Americans. Cancer Investigation, 23, 285–295.

    Article  PubMed  Google Scholar 

  • Halliday, J., Lumley, J., & Watson, L. (1995). Comparison of women who do and do not have amniocentesis or chorionic villus sampling. Lancet, 345, 704–709.

    Article  CAS  PubMed  Google Scholar 

  • Hietala, M., Hakonen, A., Aro, A. R., Niemela, P., Peltonen, L., & Aula, P. (1995). Attitudes towards genetic testing among the general population and relatives of patients with a severe genetic disease: a survey from Finland. The American Journal of Human Genetics, 56, 1493–1500.

    CAS  PubMed  Google Scholar 

  • I.S.T.A.T. (2008). Tavole di dati [Tables Data]. Retrieved on July 2010 from https://doi.org/www.istat.it/

  • Ishiyama, I., Nagai, A., Muto, K., Tamakoshi, A., Kokado, M., Mimura, K., Tanzawa, T., & Yamagata, Z. (2008). Relationship between public attitudes toward genomic studies related to medicine and their level of genomic literacy in Japan. American Journal of Medical Genetics, 146A(13), 1696–1706. Part A.

    Article  PubMed  Google Scholar 

  • Italian Law 40/2004, n.40. Gazzetta Ufficiale n.45 (February 24, 2004).

  • Italian National Institute of Health (1998). Linee guida per test genetici [Guidelines for genetic testing]. Retrieved from https://doi.org/www.iss.it/tege/docu/cont.php?id=72&lang=1&tipo=11

  • Ivry, T., Teman, E., & Frumkin, A. (2011). God-Sent ordeals and their discontents: Haredi ultra-orthodox Jewish women negotiate prenatal testing. Social Science & Medicine, 72, 1527–1533.

    Article  Google Scholar 

  • Janz, N., & Becker, M. H. (1984). The health belief model: a decade later. Health Education Quarterly, 11, 1–47.

    Article  CAS  PubMed  Google Scholar 

  • Jaspers, J., & Fraser, C. (1984). Attitudes and social representations. In Farr and Moscovici (Eds.) Social representations (pp. 101–123). Cambridge: Cambridge University Press.

  • Jöreskog, K. G., & Sörbom, D. (1988). Lisrel 7. A guide to the program and appications. Chicago: Spss Inc.

    Google Scholar 

  • Jöreskog, K. G., & Sörbom, D. (1996). Lisrel 8. User’s reference guide. Lincolnwood: Scientific Software International, Inc.

    Google Scholar 

  • Jöreskog, K. G., Sörbom, D., Du Toit, S., & Du Toit, M. (2001). LISREL 8: New statistical features. Lincolnwood: Scientific Software International, Inc.

    Google Scholar 

  • Keller, J. (2005). In genes we trust: the biological component of psychological essentialism and its relationship to mechanisms of motivated social cognition. Journal of Personality and Social Psychology, 85, 686–702.

    Article  Google Scholar 

  • Kind, P. M., Jones, K., & Barmby, P. (2007). Developing attitudes towards science measures. International Journal of Science Education, 29(7), 871–893.

    Article  Google Scholar 

  • Kobelka, C., Mattman, A., & Langlois, S. (2009). An evaluation of the decision-making process regarding amniocentesis following a screen-positive maternal serum screen result. Prenatal Diagnosis, 29(5), 514–519.

    Article  PubMed  Google Scholar 

  • Lanie, A. D., Jayaratne, T. E., Sheldon, J. P., Kardia, S. L. R., Anderson, E. S., Feldbaum, M., et al. (2004). Exploring the public understanding of basic genetic concepts. Journal of Genetic Counseling, 13, 305–320.

    Article  PubMed  PubMed Central  Google Scholar 

  • Learman, L. A., Kuppermann, M., Gates, E., Nease, R. F., Jr., Gildengorin, V., & Washington, A. E. (2003). Social and familial context of prenatal genetic testing decisions: are there racial/ethnic differences? American Journal of Medical Genetics, 119C, 19–26.

    Article  PubMed  Google Scholar 

  • Legare, F., St-Jacques, S., Gagnon, S., Njoya, M., Brisson, M., Fremont, P., & Rousseau, F. (2011). Prenatal screening for Down syndrome: a survey of willingness in women and family physicians to engage in shared decision-making. Prenatal Diagnosis, 31, 319–326. doi:https://doi.org/10.1002/pd.2624.

    Article  PubMed  Google Scholar 

  • Lerman, C., Marshall, J., Audrain, J., & Gomez-Caminero, A. (1996). Genetic testing for colon cancer susceptibility: anticipated reactions of patients and challenges to providers. International Journal of Cancer, 69(1), 58–61.

    Article  CAS  PubMed  Google Scholar 

  • Lerman, C., Hughes, C., Trock, B. J., Myers, R. E., Main, D., Bonney, A., Abbaszadegan, M. R., Harty, A. E., Franklin, B. A., Lynch, J. F., & Lynch, H. T. (1999). Genetic testing in families with hereditary nonpolyposis colon cancer. Journal of the American Medical Association, 281, 1618–1622.

    Article  CAS  PubMed  Google Scholar 

  • Leung, T. N., Ching Chau, M. M., Chang, J. J., Leung, T. Y., Fung, T. Y., & Lau, T. K. (2004). Attitudes towards termination of pregnancy among Hong Kong Chinese women attending prenatal diagnosis counselling clinic. Prenatal Diagnosis, 24, 546–551. doi:https://doi.org/10.1002/pd.950.

    Article  PubMed  Google Scholar 

  • MacCallum, R. C., & Hong, S. (1997). Power analysis in covariance structure modeling using GFI and AGFI. Multivariate Behavioral Research, 32, 193–210.

    Article  CAS  PubMed  Google Scholar 

  • MacCallum, R. C., Browne, M. W., & Sugawara, H. M. (1996). Power analysis and determination of sample size for covariance structure modeling. Psychological Methods, 1, 130–149.

    Article  Google Scholar 

  • Marteau, T. M., Kidd, J., Cook, R., Michie, S., Johnston, M., Slack, J., et al. (1991). Perceived risk not actual risk predicts uptake of amniocentesis. British Journal of Obstetrics and Gynaecology, 98, 282–286.

    Article  CAS  PubMed  Google Scholar 

  • Michie, S., Drake, H., Bobrow, M., & Marteau, T. (1995). A comparison of public and professionals’ attitudes towards genetic developments. Public Understanding of Science, 4, 243–253.

    Article  Google Scholar 

  • Michie, S., Dormandy, E., French, D. P., & Marteau, T. M. (2004). Using the theory of planned behaviour to predict screening uptake in two contexts. Psychology and Health, 19(6), 705–718.

    Article  Google Scholar 

  • Mishori Dery, A., Carmi, R., & Shoham Vardi, I. (2008). Attitudes toward the acceptability of reasons for pregnancytermination due to fetal abnormalities among prenatal care providers and consumers in Israel. Prenatal Diagnosis, 28, 518–524. doi:https://doi.org/10.1002/pd.2017.

    Article  PubMed  Google Scholar 

  • N.I.H. (n.d.). on-line document. Retrieved on September 2009 from https://doi.org/www.nichd.nih.gov/publications/pubs/downsyndrome.cfm#DownSyndrome

  • OBSERVA (2008). Gli italiani e la scienza. Primo rapporto su scienza, tecnologia e opinione pubblica in Italia [Italians and Science. The First report on science, technology and public opinion in Italy]. Annuario Scienza e Società. Bologna: Il Mulino.

  • Palmonari, A. (2004). Si può pensare ad una psicologia sociale fondata sulla teoria delle rappresentazioni sociali?. In N. De Piccoli e G.P. Quaglino (a cura di), Psicologia sociale in dialogo. Scritti in onore di Piero Amerio [Social Psychology in dialogue. Writings in honour of Piero Amerio]. Milano, Unicopli.

  • Press, N., & Browner, C. H. (1997). Why women say yes to prenatal diagnosis. Social Science & Medicine, 45, 979–989.

    Article  CAS  Google Scholar 

  • Raz, A. E., Atar, M., Rodnay, M., Shoham-Vardi, I., & Carmi, R. (2003). Between acculturation and ambivalence: knowledge of genetics and attitudes towards genetic testing in a consanguineous Bedouin community. Community Genetics, 6, 88–95.

    PubMed  Google Scholar 

  • Reid, B., Sinclair, M., Barr, O., Dobbs, F., & Crealey, G. (2009). A meta-synthesis of pregnant women’s decision-making processes with regard to antenatal screening for Down syndrome. Social Science & Medicine, 69(11), 1561–1573.

    Article  Google Scholar 

  • Rose, A. L., Peters, N., Shea, J. A., & Armstrong, K. (2005). Attitudes and misconceptions about predictive genetic testing for cancer risk. Community Genetics, 8(3), 145–151.

    PubMed  Google Scholar 

  • Rouquette, M-L., & Flament, C. (2003) Anatomie des idée ordinaries [Anatomy of everyday ideas]. Paris, A.Colin.

  • Rowe, R., Puddicombe, D., Hockley, C., & Redshaw, M. (2008). Offer and uptake of prenatal screening for Down syndrome in women from different social and ethnic backgrounds. Prenatal Diagnosis, 28, 1245–1250.

    Article  PubMed  Google Scholar 

  • S.I.G.U. (2004). Censimento SIGU 2002—Strutture di genetica medica e test genetici in Italia [Census SIGU 2002- Medical genetics structures and genetic tests in Italy]. Retrieved on March 2008 from https://doi.org/sigu.accmed.org/sigu/html/documenti_altri/2004_2_3_analysis.pdf

  • S.I.Di.P. (2006). Linee guida sulle tecniche invasive in diagnosi prenatale [Guidelines on prenatal diagnosis invasive techniques]. Retrieved on September 2009 from https://doi.org/194.244.42.60/ilfetonew/Articoli/LineeGuida/LINEE%20GUIDA%20No.1%20LIBRETTO.pdf

  • Sapp, J. C., Chandros Hull, S., Duffer, S., Zornetzer, S., Sutton, E., Marteau, T. M., & Bowles Biesecker, B. (2010). Ambivalence toward undergoing invasive prenatal testing: an exploration of its origins. Prenatal Diagnosis, 30(1), 77–82.

    PubMed  PubMed Central  Google Scholar 

  • Saucier, J. B., Johnston, D., Wicklund, C. A., Robbins-Furman, P., Hecht, J. T., & Monga, M. (2005). Racial-ethnic differences in genetic amniocentesis uptake. Journal of Genetic Counseling, 14(3), 189–195.

    Article  PubMed  Google Scholar 

  • Schermelleh-Engel, K., Moosbrugger, H., & Müller, H. (2003). Evaluating the fit of structural equation models: test of significance and descriptive goodness-of-fit measures. Methods of Psychological Research—Online, 8(2), 23–74.

    Google Scholar 

  • Schwartz, M. D., Hughes, C., Roth, J., Main, D., Peshkin, B. N., Isaacs, C., et al. (2000). Spiritual faith and genetic testing decisions among high-risk breast cancer probands. Cancer Epidemiology, Biomarkers & Prevention, 9(4), 381–385.

    CAS  Google Scholar 

  • Seror, V., & Ville, Y. (2010). Women’s attitudes to the successive decisions possibly involved in prenatal screening for Down syndrome: how consistent with their actual decisions? Prenatal Diagnosis, 30, 1086–1093. doi:https://doi.org/10.1002/pd.2616.

    Article  PubMed  Google Scholar 

  • Seth, S. G., Goka, T., Harbison, A., Hollier, L., Peterson, S., Ramondetta, L., & Noblin, S. J. (2011). Exploring the role of religiosity and spirituality in amniocentesis decision-making among Latinas. Journal of Genetic Counseling, 20(6), 660–673.

    Article  PubMed  Google Scholar 

  • Sher, C., Romano-Zelekha, O., Green, M. S., & Shohat, T. (2003). Factors affecting performance of prenatal genetic testing by Israeli Jewish women. American Journal of Medical Genetics, 30, 418–422.

    Article  Google Scholar 

  • Shoham-Vardi, I., Weiner, N., Weitzman, D., & Levcovich, A. (2004). Termination of pregnancy: attitudes and behavior of women in a traditional society. Prenatal Diagnosis, 24(11), 869–875.

    Article  CAS  PubMed  Google Scholar 

  • Singer, E., Van Hoewyk, J., & Antonucci, T. C. (2005). U.S. attitudes toward genetic testing, 1990–2000. International Journal of Public Opinion Research, 17(1), 113–125.

    Article  Google Scholar 

  • Singer, E., Couper, M. P., Raghunathan, T., Van Hoewyk, J., & Antonucci, T. (2008). Trends in US attitudes toward genetic testing, 1990–2004. Public Opinion Quarterly, 72(3), 446–458.

    Article  PubMed  PubMed Central  Google Scholar 

  • Smerecnik, C. M., Mesters, I., de Vries, N. K., & de Vries, H. (2008). Educating the general public about multifactorial genetic disease: applying a theory-based framework to understand current public knowledge. Genetic Medicine, 10, 251–258.

    Article  Google Scholar 

  • Sturgis, P. J., & Allum, N. C. (2001). Gender differences in scientific knowledge and attitudes toward science: reply to Hayes and Tariq. Public Understanding of Science, 10(4), 427–430.

    Article  Google Scholar 

  • Tercyak, K. P., Johnson, S. B., Roberts, S. F., & Cruz, A. C. (2001). Psychological response to prenatal genetic counseling and amniocentesis. Patient Education and Counseling, 43, 73–84.

    Article  CAS  PubMed  Google Scholar 

  • Thomas, S., Herbert, D., Street, A., Barnes, C., Boal, J., & Komesaroff, P. (2007). Attitudes towards and beliefs about genetic testing in the haemophilia community: a qualitative study. Haemophilia, 13(5), 633–641.

    Article  CAS  PubMed  Google Scholar 

  • Toiviainen, H., Jallinoja, P., Aro, A. R., & Hemminki, E. (2003). Medical and lay attitudes towards genetic screening and testing in Finland. European Journal of Human Genetics, 11, 565–572.

    Article  PubMed  Google Scholar 

  • Turoldo, F. (2007). Non esiste un gene per lo spirito umano: considerazioni filosofiche ed etiche sui test genetici in fase prenatale. Studi Zancan, 2, 120–132.

    Google Scholar 

  • van den Berg, M., Timmermans, D. R. M., Kleinveld, J. H., van Eijk, J. Th., Knol, D. L., van der Wal, G., & van Vugt, J. M. G. (2007). Are counsellors’ attitudes influencing pregnant women’s attitudes and decisions on prenatal screening? Prenatal Diagnosis, 27, 518–524. doi:https://doi.org/10.1002/pd.1720.

    Article  PubMed  Google Scholar 

  • Vergani, P., Locatelli, A., Biffi, A., Ciriello, E., Zagarella, A., Pezzullo, J. C., & Ghidini, A. (2002). Factors affecting the decision regarding amniocentesis in women at genetic risk because of age 35 years or older. Prenatal Diagnosis, 22(9), 769–774.

    Article  PubMed  Google Scholar 

  • Vernon, S. W., Gritz, E. R., Peterson, S. K., Perz, C. A., Marani, S., Amos, C. I., & Baile, W. F. (1999). Intention to learn results of genetic testing for hereditary colon cancer. Cancer Epidemiology, Biomarkers & Prevention, 8, 353–360.

    CAS  Google Scholar 

  • Wilson, J. L., Ferguson, G. M., & Thorn, J. M. (2011). Genetic testing likelihood: the impact of abortion views and quality of life information on women’s decisions. Journal of Genetic Counseling, 20(2), 143–156.

    Article  PubMed  Google Scholar 

  • Wynne, B. (1995). Public understanding of science. In S. Jasanoff, G. E. Markle, J. C. Petersen, & T. Pinch (Eds.), Handbook of science and technology studies (361–388). Thousand Oaks: Sage.

    Google Scholar 

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  1. University G. d’Annunzio, Chieti-Pescara, Italy

    Monica Pivetti

  2. University of Bologna, Bologna, Italy

    Giannino Melotti

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Pivetti, M., Melotti, G. Prenatal Genetic Testing: An Investigation of Determining Factors Affecting the Decision-Making Process. J Genet Counsel 22, 76–89 (2013). https://doi.org/10.1007/s10897-012-9498-6

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