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Template Synthesis, Spectral, Thermal and Glucose Sensing of Pr3+ Complexes of Metformin Schiff-Bases

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Abstract

Schiff-bases of metformin with each of salicylaldehyde (HL1); 2,3-dihydroxybenzaldehyde (H2L2); 2,4-dihydroxybenzaldehyde (H2L3); 2,5-dihydroxybenzaldehyde (H2L4); 3,4-dihydroxybenzaldehyde (H2L5) and 2-hydroxynaphthaldehyde (HL6) and their complexes with Pr(III) were synthesized by template reaction. The complexes were characterized through elemental analysis, conductivity and magnetic moment measurements, IR, UV-Vis., fluorescence, GC-MS and XRD spectroscopy. The complexes exhibit a series of characteristic emission bands for Pr3+ ion in the 481-472 and 590-580 nm range with a 318-332 nm excitation source. The complexes have eight coordinated structure with the formulae [PrL1-4,6(NO3)2(H2O)3].nH2O where n = 1, 1½, 3, 4, 4 and [PrL5(NO3)(H2O)5].2H2O. The suggested stereochemistry was confirmed using TGA, DTG and DTA analysis and a mechanism for thermal decomposition was proposed. Coates-Redfern equation was used to calculate kinetic and thermodynamic parameters of the main decomposition step. The utility of the complexes towards the detection of glucose at physiologically relevant pH in phosphate buffer using UV-Vis and fluorescence spectroscopy as well as viscosity measurements are tried where the association constants were calculated.

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Authors and Affiliations

  1. Department of Science and Mathematics Engineering, Faculty of Petroleum and Mining Engineering, Suez University, Suez, Egypt

    Marwa Mahmoud

  2. Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, Egypt

    Enas Abdel-Salam & Shehab Sallam

  3. Holding Company for Water & Wastewater, Ismailia, Egypt

    Mahmoud Abou-Elmagd

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  1. Marwa Mahmoud
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  2. Enas Abdel-Salam
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  4. Shehab Sallam
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Correspondence to Shehab Sallam.

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Supplementary data related to this article contain representative examples of: IR spectra (S1and S2), UV-Vis spectra (S3 and S4), fluorescence spectra (S5 and S6), mass spectra (S7) of the complexes.

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Mahmoud, M., Abdel-Salam, E., Abou-Elmagd, M. et al. Template Synthesis, Spectral, Thermal and Glucose Sensing of Pr3+ Complexes of Metformin Schiff-Bases. J Fluoresc 29, 319–333 (2019). https://doi.org/10.1007/s10895-018-02341-5

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