Abstract
The new 3H-imidazo[4,5-a]acridine-11-carbonitriles were prepared from the reaction of 1-alkyl-5-nitro-1H-benzoimidazoles with 2-(4-methoxyphenyl)acetonitrile and benzyl cyanide by nucleophilic substitution of hydrogen in high yields. Physical spectral and analytical data have confirmed the structures of the synthesized dyes. The optical and solvatochromic properties of these compounds were investigated and the results showed that they show very interesting photophysical properties. Density functional theory (DFT) calculations of fluorescent dyes were performed to provide the optimized geometries and relevant frontier orbitals. Furthermore, intra- and intermolecular interactions in fluorescent imidazo[4,5-a]acridines were evaluated by AIM (Atoms in Molecules) analysis.
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Hunger K (2003) In industrial dyes. WILEY-VCH Verlag, Weinheim, pp 569–572
Dmitry A, Pavel A (2003) Dipyrrolyl quinoxalines with extended chromophores are efficient fluorimetric sensors for pyrophosphate. Chem Commun 12:1394
Gold H, Venkataraman H (1971) Ed. Pergamon, New York, Academic Press, pp 535–542
Belgodere E, Bossio R, Chimichi S, Passini V, Pepino R (1985) Synthesis and fluorescence of some thiazole and benzothiazole derivatives. Dyes Pigments 4:59
Kalle AG (1962) British patent, 895(001). Chem Abstr 57:14578
Fridman N, Kaftory M, Speiser S (2007) Structures and photophysics of lophine and double lophine derivatives. Sensors Actuators B 126:107
Karolak-Wojciechowska J, Mrozek A, Czylkowski R, Tekiner-Gulbas B, Ak- Sener E, Yalcin I (2007) Crystal structure and molecular mechanics modelling of 2-(4-Amino-3-benzyl-2-thioxo-2, 3-dihydrothiazol-5-yl)benzoxazole. J Mol Struct 839:125
Pan WL, Tan HB, Chen Y, Mu DH, Liu HB, Wan YQ et al (2008) The synthesis and preliminary optical study of 1-alkyl-2,4,5-triphenylimidazole derivatives. Dyes Pigments 76:17
Um SI (2007) The synthesis and properties of benzoxazole fluorescent brighteners for application to polyester fibers. Dyes Pigments 75:185
Karagöz F, Güney O, Kandaz M, Bilgiçli AT (2012) Acridine-derivated receptor for selective mercury binding based on chelation-enhanced fluorescence effect. J Lumin 132:2736
Ferreira APG, Frederice R, Janssen KPF, Gehlen MH (2011) Dually fluorescent silica nanoparticles. J Lumin 131:888
Preston P N (1980) The chemistry of heterocyclic compounds, benzimidazoles and cogeneric tricyclic compounds. John Wiley & Sons, Part 1, Volume 40, pp 87–105
Frisch MJ, Trucks GW, Schlegel HB, Scuseria GE et al (1998) Gaussian 98, revision A.7. Gaussian, Inc, Pittsburgh PA
Lee C, Yang W, Parr RG (1988) Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. Phys Rev B 37:785
Tomasi J, Cammi R (1995) Remarks on the use of the apparent surface charges (ASC) methods in solvation problems: iterative versus matrix-inversion procedures and the renormalization of the apparent charges. J Comput Chem 16:1449
Davis RB, Pizzini LC (1960) Condensation of aromatic nitro compounds with acrylacetonitriles. J Org Chem 25:1884
Sahraei R, Pordel M, Behmadi H, Razavi B (2013) Synthesis of a new class of strongly fluorescent heterocyclic compounds: 3H-imidazo [4, 5-a] acridine-11-carbonitriles. J Lumin 136:334
Pordel M (2012) Synthesis of new fluorescent compounds from benzimidazole. J Chem Res 36:595
Umberger JQ, LaMer VK (1945) The kinetics of diffusion controlled molecular and ionic reactions in solution as determined by measurements of the quenching of fluorescence. J Am Chem Soc 67:1099
Espinosa E, Molins E (2000) About the evaluation of the local kinetic, potential and total energy densities in closed-shell interactions. J Chem Phys 113:5686
Bader R F (1990) Atoms in molecules: a quantum theory. International series of monographs on chemistry 22, in, Oxford University Press, Oxford
Vener M, Manaev A, Egorova A, Tsirelson V (2007) QTAIM study of strong H-bonds with the OH ⊙ ⊙ ⊙ A Fragment (A = O, N) in three-dimensional periodical crystals. J Phys Chem A 111:1155
Mata I, Alkorta I, Molins E, Espinosa E (2010) Universal features of the electron density distribution in hydrogen-bonding regions: a comprehensive study involving H⋅⋅⋅X (X = H, C, N, O, F, S, Cl, π) interactions. Chem Eur J 16:2442
Krygowski TM, Zachara-Horeglad JE, Palusiak M, Pelloni S, Lazzeretti P (2008) Relation between π-electron localization/delocalization and H-bond strength in derivatives of o-hydroxy-Schiff Bases. J Org Chem 73:2138
Li X, Wang Y, Zheng S, Meng L (2012) Substituent effects on the intramolecular hydrogen bond in 1-hydroxyanthraquinone: AIM and NBO analyses. Struct Chem 23:1233
Bader RF, Carroll MT, Cheeseman JR, Chang C (1987) Properties of atoms in molecules: atomic volumes. J Am Chem Soc 109:7968
Mitra S, Chandra AK, Gashnga PM, Jenkins S, Kirk SR (2012) Exploring hydrogen bond in the excited state leading toward intramolecular proton transfer: detailed analysis of the structure and charge density topology along the reaction path using QTAIM. J Mol Model 18:4225
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Maroofi, V., Pordel, M., Chegini, H. et al. Synthesis, Spectral Studies and Quantum-Chemical Investigations on the Powerful Fluorophores: Imidazo[4,5-a]acridines. J Fluoresc 25, 1235–1243 (2015). https://doi.org/10.1007/s10895-015-1611-4
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DOI: https://doi.org/10.1007/s10895-015-1611-4