Abstract
The rheological properties of the whole blood and plasma of patients with myocardial ischemia and diabetes mellitus and of donors have been investigated using a Couette rotational viscosimeter at a temperature of 25°C in the range of rates of shear of 0.5–60 sec−1. The rheological analysis was performed with the use of the Quemada relation. The functional state of the endothelium and some biochemical indices of the blood of these patients were investigated. It is shown that in patients with myocardial ischemia and diabetes mellitus, accompanied by dyslipemia and endocrine disturbances, rheological derangements and endothelial dysfunction develop.
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A. Barnes and E. Willars, in: S. Chien, J. Dormandy, E. Ernst, and A. Matrai, Diabetes. Clinical Hemorheology, Martinus Nijhoff Pub., Dordrecht (1987), pp. 275–309.
D. E. McMillan, Hemorheological studies in the diabetes control and complications trial, Clin. Hemorheol., 13, 147–154 (1993).
C. Le Devehat, M. Boisseau, M. Vimeux, et al., Hemorheological factors in the pathophysiology of venous diseases, Clin. Hemorheol., 9, 861–870 (1989).
O. K. Baskurt, Pathophysiological significance of blood rheology, Turk. J. Med. Sci., 33, 347–355 (2003).
M. Sh. Shakhmalova, M. V. Shestakova, L. A. Chugunova, and I. I. Dedov, Vasoactive factors of vasa endothelum in proteins with insulin-independent renal diabetes, Terapevt. Arkhiv, No. 6, 43–45 (1996).
D. S. Celemajer, K. E. Sorensen, V. M. Gooch, et al., Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis, The Lancet, 340, 1111–1115 (1992).
F. J. Walburn and D. J. Schneck, A constitutive equation for whole human blood, Biorheology, 13, 201–210 (1976).
G. D. O. Lowe and J. C. Barbenel, Plasma and blood viscosity, in: G. D. O. Lowe, Clinical Blood Rheology, Vol. 1, CRC Press, Boca Raton, Florida (1988), pp. 11–44.
A. M. Bubenchikov and S. E. Kornelik, Modern Mathematical Representation of the Cardiovascular System. Manual [in Russian], Izd. Tomsk. Univ., Tomsk (2001).
P. Sherman (Ed.), Emulsion Science, Academic Press, London-New York (1968).
J. A. Sirs, The flow of human blood through capillary tubes, J. Physiol., 442, 569–583 (1991).
A. S. Popel and G. Enden, An analytic solution for steady flow of Quemada fluid in a circular tube, Rheol. Acta, 32, 422–426 (1993).
D. Quemada, Rheology of concentrated disperse systems and minimum energy dissipation principle. I. Viscosity concentration relationship, Rheol. Acta, 16, 82–94 (1977).
D. Quemada, in: J. Cases-Vasquez and J. Lebon, Lecture Notes in Physics: Stability of Thermodynamic Systems, Springer, Berlin (1982).
G. R. Cokelet and H. L. Goldsmith, Decreased hydrodynamic resistance in the two-phase flow of blood through small vertical tubes at low flow rates, Circulation Res., 68, 1–17 (1991).
J.-B. Zhang and Z.-B. Kuang, Study on blood constitutive parameters in different blood constitutive equations, J. Biomech., 33, 355–360 (2000).
L. A. Faitelson and E. E. Jakobsons, Aggregation of erythrocytes into column structures (“monetary columns”) and blood rheology, Inzh.-Fiz. Zh., 76, No. 3, 214–225 (2003).
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Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 79, No. 1, pp. 96–101, January–February, 2006.
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Shul’man, Z.P., Mansurov, V.A., Mit’kovskaya, N.P. et al. Rheological changes in the blood and plasma of patients with myocardial ischemia and diabetes mellitus and dysfunction of their endothelium. J Eng Phys Thermophys 79, 99–104 (2006). https://doi.org/10.1007/s10891-006-0072-7
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DOI: https://doi.org/10.1007/s10891-006-0072-7