Abstract
The chemical composition of Taxodium distichum cones and the antifungal activities of twelve diterpenoids against two wood decay fungi, Trametes versicolor (white-rot) and Fomitopsis palustris (brown-rot) were examined. The chemical composition of the major extractive fraction, the n-C6H14 extract, was evaluated and its antifungal properties were identified. Twelve diterpenoids including ten abietane-type components were isolated from the n-C6H14 extract: 6,7-dehydroferruginol (1), ferruginol (2), 6,7-dehydroroyleanone (3), sandaracopimaric acid (4), taxodione (5), taxodal (6), taxodone (7), sugiol (8), xanthoperol (9), salvinolone (10), 5,6-dehydrosugiol (11), and 14-deoxycoleon U (12). Compounds 5 and 12 were highly active against both wood-decay fungi. In particular, the activities of these compounds against F. palustris were potent. The results suggest that the position and the number of hydroxyl groups on abietane-type structures may be related to antifungal activities against T. versicolor and F. palustris.
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Acknowledgement
The authors thank Dr. Nobuhiro Sekine (Institute of Wood Technology, Akita Prefectural University) and Dr. Ganis Lukmandaru (Department of Forest Product Technology, Gadjah Mada University) for research counsel, as well as Dr. Lopez Caceres Maximo Larry (The United Graduate School of Agricultural Science, Iwate University) and Douglas Jones for language support.
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Kusumoto, N., Ashitani, T., Murayama, T. et al. Antifungal Abietane-Type Diterpenes from the Cones of Taxodium distichum Rich. J Chem Ecol 36, 1381–1386 (2010). https://doi.org/10.1007/s10886-010-9875-2
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DOI: https://doi.org/10.1007/s10886-010-9875-2