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Homozygous IL1RN Mutation in Siblings with Deficiency of Interleukin-1 Receptor Antagonist (DIRA)

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Acknowledgements

This study was supported by DEBRA International. Carol Kelly assisted in manuscript preparation. The authors thank Dr. Sara Pajouhanfar for clinical consulting.

Author information

Author notes

  1. Vahid Ziaee, Leila Youssefian and Masoomeh Faghankhani contributed equally to this work.

Authors and Affiliations

  1. Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran

    Vahid Ziaee

  2. Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran

    Vahid Ziaee

  3. Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, 233 S. 10th Street, Suite 450 BLSB, Philadelphia, PA, 19107, USA

    Leila Youssefian, Masoomeh Faghankhani, Amir Hossein Saeidian, Hassan Vahidnezhad & Jouni Uitto

  4. Genetics, Genomics and Cancer Biology PhD Program, Thomas Jefferson University, Philadelphia, PA, USA

    Leila Youssefian & Amir Hossein Saeidian

  5. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

    Leila Youssefian

  6. Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA

    Leila Youssefian, Masoomeh Faghankhani, Amir Hossein Saeidian, Hassan Vahidnezhad & Jouni Uitto

  7. Department of Information Science, College of Computing and Informatics, Drexel University, Philadelphia, PA, USA

    Ali Jazayeri

  8. Biotechnology Research Center, Department of Molecular Medicine, Pasteur Institute of Iran, Tehran, Iran

    Hassan Vahidnezhad

Authors
  1. Vahid Ziaee
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  2. Leila Youssefian
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  3. Masoomeh Faghankhani
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  4. Ali Jazayeri
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  5. Amir Hossein Saeidian
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  6. Hassan Vahidnezhad
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  7. Jouni Uitto
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Corresponding authors

Correspondence to Hassan Vahidnezhad or Jouni Uitto.

Ethics declarations

This study was approved by the Institutional Review Board of Pasteur Institute of Tehran. The parents of patients gave their written informed consent to participate in this research project and gave their permission to publish their image.

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The authors declare that they have no conflict of interest.

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Ziaee, V., Youssefian, L., Faghankhani, M. et al. Homozygous IL1RN Mutation in Siblings with Deficiency of Interleukin-1 Receptor Antagonist (DIRA). J Clin Immunol 40, 637–642 (2020). https://doi.org/10.1007/s10875-020-00767-w

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  • DOI: https://doi.org/10.1007/s10875-020-00767-w

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