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Marine invertebrate cell culture: a decade of development

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Abstract

Since the 1970s, much work has been devoted to the development of marine invertebrate cell culture. Despite this effort there are still no established cell lines. During the last decade, more than 40 papers on primary cell culture have been published. The phyla primarily studied are porifera, cnidaria, crustacea, mollusca, echinodermata, urochordata, and cephalochordata. A variety of methods have been investigated to improve culture conditions and prolong the lifespan of cells, including use of different pretreatments, culture media, temperature, pH, and additives; genetic modification has also been investigated. In this paper we review the vast majority of work published on marine invertebrate cell culture in the last decade (2002–2012) and emphasize new trends in biotechnological applications of cell culture.

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Acknowledgments

This study was supported by a grant from the program of the State High–Tech Development Project (no. 2008AA092604) to YZ.

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  1. State Key Laboratory of Biocontrol, School of Life Sciences, Guangzhou Higher Education Mega Center, Sun Yat-sen University, Guangzhou, 510006, People’s Republic of China

    Xiaoqing Cai & Yan Zhang

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  1. Xiaoqing Cai
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  2. Yan Zhang
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Correspondence to Yan Zhang.

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Cai, X., Zhang, Y. Marine invertebrate cell culture: a decade of development. J Oceanogr 70, 405–414 (2014). https://doi.org/10.1007/s10872-014-0242-8

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