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The role of prospective memory in medication adherence: a review of an emerging literature

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Abstract

Although neurocognitive impairment is an established risk factor for medication nonadherence, standard neurocognitive tests developed for clinical purposes may not fully capture the complexities of non-adherence behavior or effectively inform theory-driven interventions. Prospective memory, an innovative cognitive construct describing one’s ability to remember to do something at a later time, is an understudied factor in the detection and remediation of medication non-adherence. This review orients researchers to the construct of prospective memory, summarizes empirical evidence for prospective memory as a risk factor for non-adherence, discusses the relative merits of current measurement techniques, and highlights potential prospective memory-focused intervention strategies. A comprehensive literature review was conducted of published empirical studies investigating prospective memory and medication adherence. Overall, reviewed studies suggest that prospective memory is an important component of medication adherence, providing incremental ecological validity over established predictors. Findings indicate that prospective memory-based interventions might be an effective means of improving adherence.

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Acknowledgments

This critical review was supported in part by National Institute of Health R01 MH73419 to Dr. Woods and National Institute of Health R34 MH084674 to Dr. Simoni. None of the authors has a financial relationship with the organizations that sponsored this research.

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Authors and Affiliations

  1. Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    Jennifer B. Zogg

  2. Department of Psychiatry, School of Medicine, University of California, San Diego, La Jolla, CA, USA

    Steven Paul Woods

  3. Department of Psychology, University of Texas at El Paso, El Paso, TX, USA

    John A. Sauceda & John S. Wiebe

  4. Department of Psychology, University of Washington, Seattle, WA, USA

    Jane M. Simoni

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  1. Jennifer B. Zogg
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Correspondence to Jennifer B. Zogg.

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Zogg, J.B., Woods, S.P., Sauceda, J.A. et al. The role of prospective memory in medication adherence: a review of an emerging literature. J Behav Med 35, 47–62 (2012). https://doi.org/10.1007/s10865-011-9341-9

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