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Paramagnetic labelling of proteins and oligonucleotides for NMR

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An Erratum to this article was published on 19 February 2011

Abstract

Paramagnetic effects offer a rich source of long-range structural restraints. Here we review current methods for site-specific tagging of proteins and oligonucleotides with paramagnetic molecules. The paramagnetic tags include nitroxide radicals and metal chelators. Particular emphasis is placed on tags suitable for site-specific and rigid attachment of lanthanide ions to macromolecules.

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Financial support by the Australian Research Council is gratefully acknowledged.

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  1. Research School of Chemistry, The Australian National University, Canberra, ACT 0200, Australia

    Xun-Cheng Su & Gottfried Otting

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  1. Xun-Cheng Su
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Correspondence to Gottfried Otting.

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An erratum to this article can be found online at http://dx.doi.org/10.1007/s10858-011-9475-7

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Su, XC., Otting, G. Paramagnetic labelling of proteins and oligonucleotides for NMR. J Biomol NMR 46, 101–112 (2010). https://doi.org/10.1007/s10858-009-9331-1

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