Skip to main content
SpringerLink
Log in

Joint academic and industrial efforts towards innovative and efficient solutions for clinical needs

  • Special Issue: ESB 2017
  • Review Article
  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

The 4th Translational Research Symposium (TRS) was organised at the annual meeting of the European Society for Biomaterials (ESB) 2017, Athens, Greece, with a focus on ‘Academia—Industry Clusters of Research for Innovation Catalysis’. Collaborations between research institutes and industry can be sustained in several ways such as: European Union (EU) funded consortiums; syndicates of academic institutes, clinicians and industries; funding from national governments; and private collaborations between universities and companies. Invited speakers from industry and research institutions presented examples of these collaborations in the translation of research ideas or concepts into marketable products. The aim of the present article is to summarize the key messages conveyed during these lectures. In particular, emphasis is put on the challenges to appropriately identify and select unmet clinical needs and their translation by ultimately implementing innovative and efficient solutions achieved through joint academic and industrial efforts.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Gehr S, Garner CC. Rescuing the lost in translation. Cell. 2016;165:765–70.

    Article  CAS  Google Scholar 

  2. Marcus HJ, et al. Regulatory approval of new medical devices: cross sectional study. BMJ. 2016;353:i2587.

    Article  Google Scholar 

  3. Ross CB, et al. From the Schools of public health. Public Health Rep. 2006;121:97–103.

    Article  Google Scholar 

  4. Chatterji AK, Fabrizio KR. Does the market for ideas influence the rate and direction of innovative activity? Evidence from the medical device industry. Strat Mgmt J. 2016;37:447–65.

    Article  Google Scholar 

  5. Bergsland J, Elle OJ, Fosse E. Barriers to medical device innovation. Med Devices (Auckl). 2014;7:205–9.

    Google Scholar 

  6. Farragher JF, et al. Translational research in kidney transplantation and the role of patient engagement. Can J Kidney Health Dis. 2015;2:42.

    Article  Google Scholar 

  7. Murphy L, and Edwards P, Bridging the valley of death: Transitioning from public to private sector financing. Colorado: National Renewable Energy Laboratory; 2003.

  8. European Commission. FP7 in Brief: How to get involved in the Framework Programme for Research. Belgium: European Commission; 2007. p 1–32.

  9. Lilja, M, et al. Co-precipitation of a therapeutic agent into hydroxyapatite coatings. Amsterdam: Stryker European Holdings I, LLC; 2016.

  10. Lilja, M, et al. Method for drug loading hydroxyapatite coated implant surfaces. Amsterdam: Stryker European Holdings I, LLC; 2016.

  11. Procter, P, et al. Method of manufacturing an implant for use in a surgical procedure. Amsterdam: Stryker European Holdings I, LLC; 2016

  12. Pujari-Palmer M, et al. Influence of cement compressive strength and porosity on augmentation performance in a model of orthopedic screw pull-out. J Mech Behav Biomed Mater. 2018;77:624–33.

    Article  Google Scholar 

  13. Sladkova M, et al. Fabrication of macroporous cement scaffolds using PEG particles: In vitro evaluation with induced pluripotent stem cell-derived mesenchymal progenitors. Mater Sci Eng C. 2016;69:640–52.

    Article  CAS  Google Scholar 

  14. Kisiel M, et al. Complexation and sequestration of BMP-2 from an ECM mimetic hyaluronan gel for improved bone formation. PLoS ONE. 2013;8:e78551.

    Article  CAS  Google Scholar 

  15. Serena E, et al. Skeletal muscle differentiation on a chip shows human donor mesoangioblasts’ efficiency in restoring dystrophin in a duchenne muscular dystrophy model. Stem Cells Transl Med. 2016;5:1676–83.

    Article  CAS  Google Scholar 

  16. Hannink G, et al. In vivo behavior of a novel injectable calcium phosphate cement compared with two other commercially available calcium phosphate cements. J Biomed Mater Res B. 2008;85:478–88.

    Article  Google Scholar 

  17. The European Parliament and The Council of The European Union, Regulation (EU) 2017/745 of the European Parliament and of the Council of 5 April 2017 on medical devices. Off J Euro Union. 2017;60:1–175..

  18. Magill SS, et al. Multistate point-prevalence survey of health care-associated infections. N Engl J Med. 2014;370:1198–208.

    Article  CAS  Google Scholar 

  19. Saadatian-Elahi M, Teyssou R, Vanhems P. Staphylococcus aureus, the major pathogen in orthopaedic and cardiac surgical site infections: a literature review. Int J Surg. 2008;6:238–45.

    Article  Google Scholar 

  20. Anderson DJ. Surgical site infections. Infect Dis Clin North Am. 2011;25:135–53.

    Article  Google Scholar 

  21. Romano CL, et al. Antibacterial coating of implants in orthopaedics and trauma: a classification proposal in an evolving panorama. J Orthop Surg Res. 2015;10:157.

    Article  Google Scholar 

  22. Hasan J, Crawford RJ, Ivanova EP. Antibacterial surfaces: the quest for a new generation of biomaterials. Trends Biotechnol. 2013;31:295–304.

    Article  CAS  Google Scholar 

  23. Guimond-Lischer S, et al. Vacuum plasma sprayed coatings using ionic silver doped hydroxyapatite powder to prevent bacterial infection of bone implants. Biointerphases. 2016;11:011012.

    Article  Google Scholar 

  24. Tsekoura E, et al. Battling bacterial infection with hexamethylene diisocyanate cross-linked and Cefaclor-loaded collagen scaffolds. Biomed Mater. 2017;12:035013.

    Article  CAS  Google Scholar 

  25. Murphy SV, Atala A. 3D bioprinting of tissues and organs. Nat Biotechnol. 2014;32:773.

    Article  CAS  Google Scholar 

  26. Ingavle GC, Leach JK. Advancements in electrospinning of polymeric nanofibrous scaffolds for tissue engineering. Tissue Eng B. 2014;20:277–93.

    Article  CAS  Google Scholar 

  27. Raimondi MT, et al. Two-photon laser polymerization: from fundamentals to biomedical application in tissue engineering and regenerative medicine. J Appl Biomater Funct Mater. 2012;10:55–65.

    Google Scholar 

  28. Ryan C, et al. An academic, clinical and industrial update on electrospun, additive manufactured and imprinted medical devices. Expert Rev Med Devices. 2015;12:601–12.

    Article  CAS  Google Scholar 

  29. Abbah S, et al. Harnessing hierarchical nano- and micro-fabrication technologies for musculoskeletal tissue engineering. Adv Health Mater. 2015;4:2488–99.

    Article  CAS  Google Scholar 

  30. Williams CG, et al. Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation. Biomaterials. 2005;26:1211–8.

    Article  CAS  Google Scholar 

  31. Ligon SC, et al. Polymers for 3D printing and customized additive manufacturing. Chem Rev. 2017;117:10212–90.

    Article  CAS  Google Scholar 

  32. Houben A, et al. Flexible oligomer spacers as the key to solid-state photopolymerization of hydrogel precursors. Mater Today Chem. 2017;4:84–89.

    Article  Google Scholar 

  33. Amoroso S, Coad A, Grassano N. European R&D networks: a snapshot from the 7th EU Framework Programme. Eco Inno New Tech. 2018;27:404–19.

    Article  Google Scholar 

  34. Colombo MG, D’Adda D, Pirelli LH. The participation of new technology-based firms in EU-funded R&D partnerships: the role of venture capital. Res Policy. 2016;45:361–75.

    Article  Google Scholar 

  35. McMurry-Heath M, Hamburg MA. Creating a space for innovative device development. Sci Transl Med. 2012;4:163fs43.

    Article  Google Scholar 

Download references

Acknowledgements

This work received funding from H2020-MSCA-ITN-2015, Tendon Therapy Train Project (Grant Agreement Number: 676338). It has also been supported from the Science Foundation Ireland, Career Development Award (Grant Agreement Number: 15/CDA/3629) and the Science Foundation Ireland and the European Regional Development Fund (Grant Agreement Number: 13/RC/2073).

Author information

Authors and Affiliations

  1. Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), National University of Galway Ireland (NUI Galway), Galway, Ireland

    Andrea De Pieri, Sofia Ribeiro, Dimitrios Tsiapalis & Dimitrios I. Zeugolis

  2. Science Foundation Ireland (SFI) Centre for Research in Medical Devices (CÚRAM), National University of Galway Ireland (NUI Galway), Galway, Ireland

    Andrea De Pieri, Sofia Ribeiro, Dimitrios Tsiapalis & Dimitrios I. Zeugolis

  3. Proxy Biomedical Ltd., Coilleach, Spiddal, Galway, Ireland

    Andrea De Pieri

  4. Medtronic Sofradim Production, Trevoux, France

    Sofia Ribeiro & Yves Bayon

  5. AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos, Switzerland

    David Eglin

  6. RMS Foundation, Bischmattstrasse 12, P.O. Box 203, 2544, Bettlach, Switzerland

    Marc Bohner

  7. Polymer Chemistry & Biomaterials Research Group, Ghent University, Krijgslaan 281 S4 Bis, Ghent, 9000, Belgium

    Peter Dubruel

  8. CPP SARL Divonne les Bains, 01220, Divonne les Bains, France

    Philip Procter

  9. Applied Materials Science, Dept Eng. Sciences, Uppsala University, 752 37, Uppsala, Sweden

    Philip Procter

Authors
  1. Andrea De Pieri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sofia Ribeiro
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Dimitrios Tsiapalis
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. David Eglin
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Marc Bohner
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Peter Dubruel
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Philip Procter
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Dimitrios I. Zeugolis
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Yves Bayon
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yves Bayon.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Andrea de Pieri, Sofia Ribeiro and Dimitrios Tsiapalis share equally first authorship.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

De Pieri, A., Ribeiro, S., Tsiapalis, D. et al. Joint academic and industrial efforts towards innovative and efficient solutions for clinical needs. J Mater Sci: Mater Med 29, 129 (2018). https://doi.org/10.1007/s10856-018-6136-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10856-018-6136-3

Search

Navigation