Abstract
Calcium silicate ceramic coatings have received considerable attention in recent years due to their excellent bioactivity and bonding strength. However, their high dissolution rates limit their practical applications. In this study, zinc incorporated calcium silicate based ceramic Ca2ZnSi2O7 coating was prepared on Ti-6Al-4V substrate via plasma spraying technology aiming to achieve higher chemical stability and additional antibacterial activity. Chemical stability of the coating was assessed by monitoring mass loss and ion release of the coating after immersion in the Tris–HCl buffer solution and examining pH value variation of the solution. Results showed that the chemical stability of zinc incorporated coating was improved significantly. Antimicrobial activity of the Ca2ZnSi2O7 coating was evaluated, and it was found that the coating exhibited 93% antibacterial ratio against Staphylococcus aureus. In addition, in vitro bioactivity and cytocompatibility were confirmed for the Ca2ZnSi2O7 coating by simulated body fluid test, MC3T3-E1 cells adhesion investigation and cytotoxicity assay.
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This study was supported by the National Natural Science Foundation of China (Grant No. 81071455) and the Fund for Key Science and Technology Program of Shanghai Science and Technology Committee (Grant No. 09441900106).
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Kai Li and Jiangming Yu are contributed equally to this work.
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Li, K., Yu, J., Xie, Y. et al. Chemical stability and antimicrobial activity of plasma sprayed bioactive Ca2ZnSi2O7 coating. J Mater Sci: Mater Med 22, 2781–2789 (2011). https://doi.org/10.1007/s10856-011-4454-9
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DOI: https://doi.org/10.1007/s10856-011-4454-9