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Antibacterial activity, optical, mechanical, thermal, and dielectric properties of L-phenylalanine fumaric acid single crystals for biomedical, optoelectronic, and photonic applications

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Abstract

A single crystal of L-Phenylalanine Fumaric Acid (LPFA) with molecular formula C9H11NO2.C4H4O4 was successfully synthesized by slow evaporation solution growth technique. The grown crystal underwent several characterizations. The single crystal X-ray diffraction analysis reveals that the synthesized sample crystallizes in the triclinic system with the space group PI. Using the UV-Vis spectral analysis, it was found that the grown crystal holds good optical quality which indicates that the crystal is transparent in the visible region with lower cut-off wavelength of 223 nm and optical band gap is found to be 5.57 eV. Using the UV-Vis spectrum, the remarkable properties such as extinction coefficient, reflectance, refractive index, electrical conductivity, optical conductivity, and electric susceptibility have been calculated. From Vickers Micro hardness, the mechanical stability of the LPFA crystal and work hardening coefficient is found to be 3.8. By thermogravimetric and differential thermal analysis, it has been analyzed that the grown crystal is having thermal stability up to 206 °C. The electrical properties have been analyzed using the dielectric studies. It has been found that the sample exhibits lower dielectric constant and dielectric loss at high frequencies which indicates good optical quality of the crystal. The antibacterial activity was investigated using four strains such as Escherichia coli, Serratia marcescens, Pseudomonas aeruginosa, and Staphylococcus aureus using Agar disk diffusion test and it has been evaluated that the sample is having strongest activity of 43 mm against Pseudomonas aeruginosa. Hence, the as grown sample is having wide applications in the field of electro-optics, water purification and bio-medicine.

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Acknowledgements

The authors are thankful to SAIF, Cochin for providing excellent research facilities.

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  1. Research Scholar, Manonmaniam Sundaranar University, Reg. No: 18123112132039, Abishekapatti, Tirunelveli, 627012, Tamil Nadu, India

    D. Abila Darling

  2. Department of Physics and Research Centre, Nesamony Memorial Christian College, Marthandam, 629165, Tamil Nadu, India

    D. Abila Darling & S. E. Joema

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Darling, D.A., Joema, S.E. Antibacterial activity, optical, mechanical, thermal, and dielectric properties of L-phenylalanine fumaric acid single crystals for biomedical, optoelectronic, and photonic applications. J Mater Sci: Mater Electron 31, 22427–22441 (2020). https://doi.org/10.1007/s10854-020-04744-2

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