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β-Cyclodextrin-grafted TEMPO-oxidized cellulose nanofibers for sustained release of essential oil

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Abstract

The present investigation deals with the development and characterization of a new controlled release packaging system for food. Novel sustained system was developed by direct grafting of beta-cyclodextrin (βCD) on the carboxyl groups of TEMPO-oxidized cellulose nanofibers (TEMPO-CNF) in aqueous solution and without using any spacer. Carvacrol, an aromatic essential oil component, was then entrapped in the ensued CD-grafted TEMPO-CNF. Successful functionalization of TEMPO-CNF was confirmed by conductometric titration, Fourier Transform Infrared Spectroscopy, and gravimetric analyses. The βCD-grafted TEMPO-CNF films exhibited sustained release of carvacrol over 150 h before reaching the equilibrium in water. Antimicrobial activity of carvacrol against Bacillus subtilis was increased (or improved by 47 h) from 3 h when using TEMPO-CNF to around (or against) 50 h when using CD-grafted TEMPO-CNF. These promising results pave the way for the development of new bio-based controlled release packaging materials with efficient antibacterial activity.

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Acknowledgements

This research was supported by new generation packaging (NEWGENPAK) Project of the Seven Framework Program of European Research under Grant Agreement No 290098. LGP2 is part of the LabEx Tec 21 (Investissements d’Avenir - Grant Agreement No ANR-11-LABX-0030) and of the Énergies du Futur and PolyNat Carnot Institutes (Investissements d’Avenir - Grant Agreements No ANR-11-CARN-007-01 and ANR-11-CARN-030-01). This research was made possible thanks to the facilities of the TekLiCell platform funded by the Région Rhône-Alpes (ERDF: European regional development fund).

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Authors and Affiliations

  1. Univ. Grenoble Alpes, LGP2, 38000, Grenoble, France

    Seema Saini, Mohamed Naceur Belgacem & Julien Bras

  2. CNRS, LGP2, 38000, Grenoble, France

    Seema Saini, Deborah Quinot, Mohamed Naceur Belgacem & Julien Bras

  3. Department of Biomaterials Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, 113-8657, Japan

    Nathalie Lavoine

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  1. Seema Saini
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  2. Deborah Quinot
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  4. Mohamed Naceur Belgacem
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  5. Julien Bras
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Correspondence to Julien Bras.

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Saini, S., Quinot, D., Lavoine, N. et al. β-Cyclodextrin-grafted TEMPO-oxidized cellulose nanofibers for sustained release of essential oil. J Mater Sci 52, 3849–3861 (2017). https://doi.org/10.1007/s10853-016-0644-7

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  • DOI: https://doi.org/10.1007/s10853-016-0644-7

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