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Effects of the molecular format of collagen on characteristics of electrospun fibres

  • Materials in New Zealand
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Abstract

Electrospinning is a process that is used to create nanofibres, which have the potential to be used in many medical and industrial applications. The molecular structure of the raw material is an important factor in determining the structure and quality of the electrospun fibres. In this study, we extracted collagen from a cold water fish species, hoki (Macruronus novaezelandiae), and prepared it in several different molecular formats (native triple helical collagen, denatured whole chains, denatured atelocollagen chains and gelatin) for electrospinning. Low molecular weight gelatin and atelocollagen did not form fibres. Treatment with 1,1,1,3,3,3 hexafluoro-2-propanol or 40% acetic acid denatured collagen molecules into intact α-chains prior to the electrospinning process. When using intact denatured collagen chains, 10% acetic acid was an effective aqueous-based solvent for producing uniform fibres. This information will be useful for the development of a non-toxic, aqueous solvent system suitable for industrial scale-up of the electrospinning process. Our results show that this low imino marine collagen is a suitable biopolymer for producing electrospun fibres.

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Acknowledgements

The authors thank Neil Buunk of Electrospinz Ltd, Blenheim, New Zealand, for the laboratory electrospinning machines. Jon Stanger is a Technology in Industry Fellow, funded by the NZ Foundation for Research Science and Technology (FRST). This study was funded by the New Zealand Institute for Plant and Food Research Ltd, and the FRST Technology for Business Growth “FibreTech” project.

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Authors and Affiliations

  1. Bioresources, Engineering and Chemistry, The New Zealand Institute for Plant & Food Research Ltd, 300 Wakefield Quay, Port Nelson, P.O. Box 5114, Nelson, 7043, New Zealand

    Kathleen Hofman, Susan Marshall & Bronwyn Hall

  2. Bioresources, Engineering and Chemistry, The New Zealand Institute for Plant & Food Research Ltd, Private Bag 4704, Christchurch, 8140, New Zealand

    Nick Tucker & Jon Stanger

  3. Department of Mechanical Engineering, University of Canterbury, Private Bag 4800, Christchurch, 8140, New Zealand

    Mark Staiger

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  1. Kathleen Hofman
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  2. Nick Tucker
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  3. Jon Stanger
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  4. Mark Staiger
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  5. Susan Marshall
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  6. Bronwyn Hall
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Correspondence to Kathleen Hofman.

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Hofman, K., Tucker, N., Stanger, J. et al. Effects of the molecular format of collagen on characteristics of electrospun fibres. J Mater Sci 47, 1148–1155 (2012). https://doi.org/10.1007/s10853-011-5775-2

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  • DOI: https://doi.org/10.1007/s10853-011-5775-2

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