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Synthesis, characterization and application of β-cyclodextrin-silica nanocomposite as potential microvessel in nucleophilic substitution reaction of phenacyl halides

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Abstract

In the present study, β-cyclodextrin-silica hybrid is synthesized as a novel, efficient and eco-friendly microvessel and solid–liquid phase-transfer catalyst. This molecular host system was applied for nucleophilic substitution reaction of phenacyl halides in water. No evidence was observed for the formation of by-product for example isothiocyanate or alcohol. Also the products were obtained in pure form without further purification. The structure and morphology of the obtained system were investigated by infrared spectroscopy, powder X-ray diffraction, scanning electron microscopy, transmission electron microscopy, thermogravimetric analysis and differential thermal analysis techniques. The surface porosity of the synthesized catalyst was evaluated from the nitrogen adsorption isotherm. All the results provided evidence for incorporation of β-cyclodextrin inside silica pores.

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Acknowledgments

We are grateful to the Research Council of Shahid Chamran University for financial support.

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Authors and Affiliations

  1. Chemistry Department, College of Science, Shahid Chamran University, 61357-4-3169, Ahvaz, Iran

    Ali Reza Kiasat & Simin Nazari

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  1. Ali Reza Kiasat
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  2. Simin Nazari
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Correspondence to Ali Reza Kiasat.

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Kiasat, A.R., Nazari, S. Synthesis, characterization and application of β-cyclodextrin-silica nanocomposite as potential microvessel in nucleophilic substitution reaction of phenacyl halides. J Incl Phenom Macrocycl Chem 77, 429–438 (2013). https://doi.org/10.1007/s10847-012-0263-0

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