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Supramolecular end-group separation of linear polymers with different terminals through host–guest interaction

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Abstract

By increasing the hydrophobicity of end group, the complexation rate between α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG) derivative speeds up greatly. Based on such a huge difference of complexation kinetics, the PEG derivative with palmityloxy terminal (PEG-C16) can be successfully separated from a carboxylic acid end-functionalized analogue (PEG-COOH) by once supramolecular purification. Adding α-CD into the aqueous solution of PEG-C16/PEG-COOH mixture, PEG-C16 is encapsulated into α-CD cavity to form the crystalline inclusion complex in a very short time, while almost all of PEG-COOH molecules are still reserved in the aqueous solution. After dichloromethane extraction, the pure PEG-C16 is obtained. Moreover, the host CD can be recycled. Thus, it is an efficient green way to separate and purify the linear polymers with different terminal functionality.

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Acknowledgements

The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China (20574044, 20744002 and 50633010). This work was also partially sponsored by NCET, Shanghai Rising-Star Program (06QA14029).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People’s Republic of China

    Jie Xue, Li Zhou, Peng He, Xinyuan Zhu & Deyue Yan

  2. Instrumental Analysis Center, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People’s Republic of China

    Xinyuan Zhu

  3. Department of Chemistry, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan, 430072, People’s Republic of China

    Xulin Jiang

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  1. Jie Xue
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  2. Li Zhou
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Correspondence to Xinyuan Zhu.

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Xue, J., Zhou, L., He, P. et al. Supramolecular end-group separation of linear polymers with different terminals through host–guest interaction. J Incl Phenom Macrocycl Chem 61, 83–88 (2008). https://doi.org/10.1007/s10847-007-9397-x

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  • DOI: https://doi.org/10.1007/s10847-007-9397-x

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