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Cardiac autonomic function in metabolic syndrome: a comparison of ethnic Turkish and Japanese patients

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Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

Background

Metabolic syndrome (MetS) prevalence shows some differences at various regions of the world in terms of race and ethnicity. The cardiac autonomic functions between Turkish and Japanese MetS patients with heart rate turbulence (HRT) and heart rate variability (HRV) were compared as the aim of this study.

Methods

This study consists of 149 nondiabetic subjects with MetS. All patients were further classified into subgroups based on ethnicity (76 from Turkey, 73 from Japan). Twenty-four-hour ambulatory Holter ECG recording was applied to all subjects whose HRV and HRT (total onset (TO), total slope (TS)) parameters were analyzed.

Results

The waist circumference was the only demographic parameter that was significantly different between the Turkish and Japanese patients with MetS (99.31 ± 6.12 vs 91.12 ± 6.89 for men and 91.48 ± 7.45 vs 86.26 ± 5.78 for woman; p < 0.001 and <0.001). There was a significant difference between Turkish and Japanese patients with MetS in terms of the HRT values. (TO Turkish, 0.77 ± 0.19 %; TO Japanese, 0.49 ± 1.03 %, p = 0.031; TS Turkish, 1.93 ± 1.26; TS Japanese, 2.44 ± 1.37, p = 0.041, respectively). As for HRV parameters, standard deviation of all NN intervals index was only different between Turkish and Japanese patients with MetS (90.79 ± 58.94, 128.18 ± 105.30; p = 0.034, respectively).

Conclusion

HRT and some HRV scores of ethnic Turkish MetS patients are worse than the scores of ethnic Japan MetS patients. We think that these differences are related to the central obesity.

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Authors and Affiliations

  1. Cardiology Department, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey

    Alim Erdem & Mehmet Yazıcı

  2. Cardiology Department, Sivas State Hospital, Sivas, Turkey

    Alim Erdem

  3. International Heart Center, Cardiology Department, Saitama Medical University, Saitama, Japan

    Alim Erdem, Masahiro Uenishi, Kazuo Matsumoto, Zekeriya Küçükdurmaz & Ritsushi Kato

  4. Internal Medicine Department, Sivas State Hospital, Sivas, Turkey

    Safak Sahin

  5. Beşkavaklar Mah. Ulubatlı Sok., Anıl Apt. No:20 Daire:1 Kat:1, 14200, Bolu, Turkey

    Alim Erdem

Authors
  1. Alim Erdem
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  2. Masahiro Uenishi
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  3. Kazuo Matsumoto
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  4. Zekeriya Küçükdurmaz
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  5. Ritsushi Kato
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  6. Safak Sahin
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  7. Mehmet Yazıcı
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Correspondence to Alim Erdem.

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Erdem, A., Uenishi, M., Matsumoto, K. et al. Cardiac autonomic function in metabolic syndrome: a comparison of ethnic Turkish and Japanese patients. J Interv Card Electrophysiol 35, 253–258 (2012). https://doi.org/10.1007/s10840-012-9741-y

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  • DOI: https://doi.org/10.1007/s10840-012-9741-y

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