Skip to main content
SpringerLink
Log in

Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed

  • Commentary
  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. American College of Obstetricians and Gynecologists Committee on Gynecologic Practice and Practice Committee. Female age-related fertility decline. Committee Opinion No. 589. Fertil Steril. 2014;101:633–4.

    Article  Google Scholar 

  2. Verlinsky Y, Cieslak J, Ivakhnenko V, Evsikov S, Wof G, White M, et al. Preimplantation diagnosis of common aneuploidies by the first- and second-polar body FISG analysis. J Assist Reprod Genet. 1998;15:285–9.

    Article  CAS  Google Scholar 

  3. Mastenbroek S, Twisk M, van Echten-Arends J, Sikkema-Raddatz B, Korevaar JC, Verhoeve HR, et al. In vitro fertilization with preimplantation genetic screening. N Engl J Med. 2007;357(1):9–17.

    Article  CAS  Google Scholar 

  4. Mastenbroek S, Twisk M, van der Veen F, Repping S. Preimplantation genetic screening: a systematic review. Hum Reprod Update. 2011;17:454–66.

    Article  CAS  Google Scholar 

  5. Orvieto R, Gleicher N. Should preimplantation genetic screening (PGS) be implemented to routine IVF practice? J Assist Reprod Genet. 2016;33(14):1445–8.

    Article  Google Scholar 

  6. Dahdouh EM, Balayla J, Garcia-Velasco JA. Comprehensive chromosome screening improves embryo selection: a meta-analysis. Fertil Steril. 2015;104:1503–12.

    Article  Google Scholar 

  7. Gleicher N, Kushnir V, Barad DH. The impact of patient preselection on reported IVF outcomes. J Assist Reprod Genet. 2016;33:455–9.

    Article  Google Scholar 

  8. Munné S, Kaplan B, Frattarelli JL, Child T, Nakhuda G, Shamma FN, et al. Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial. Fertil Steril. 2019;S0015–0282(19):31979. https://doi.org/10.1016/j.fertnstert.2019.07.1346.

    Article  CAS  Google Scholar 

  9. Kang HJ, Melnick AP, Stewart JD, Rosenwaks Z. Preimplantation genetic screening: who benefits? Fertil Steril. 2016;106:597–602.

    Article  Google Scholar 

  10. Rubio C, Bellver J, Rodrigo L, Castillón G, Guillén A, Vidal C, et al. In vitro fertilization with preimplantation genetic diagnosis for aneuploidies in advanced maternal age: a randomized, controlled study. Fertil Steril. 2017;107(5):1122–9.

    Article  Google Scholar 

  11. Orvieto R. Preimplantation genetic screening- the required RCT that has not yet been carried out. Reprod Biol Endocrinol. 2016;14:35.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel

    Raoul Orvieto

  2. The Tarnesby-Tarnowski Chair for Family Planning and Fertility Regulation, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel

    Raoul Orvieto

  3. The Center for Human Reproduction, New York, NY, 10021, USA

    Norbert Gleicher

  4. Foundation for Reproductive Medicine, New York, NY, 10021, USA

    Norbert Gleicher

  5. Stem Cell Biology and Molecular Embryology Laboratory, The Rockefeller University, New York, NY, 10016, USA

    Norbert Gleicher

  6. Department of Obstetrics and Gynecology, Vienna University of Medicine, 1090, Vienna, Austria

    Norbert Gleicher

Authors
  1. Raoul Orvieto
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Norbert Gleicher
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Raoul Orvieto.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Orvieto, R., Gleicher, N. Preimplantation genetic testing for aneuploidy (PGT-A)—finally revealed. J Assist Reprod Genet 37, 669–672 (2020). https://doi.org/10.1007/s10815-020-01705-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10815-020-01705-w

Keywords

Search

Navigation