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Are we ready to inject? Individualized LC-CUSUM training in ICSI

  • Assisted Reproduction Technologies
  • Published:
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Abstract

Purpose

The objective of this prospective, single center study was to develop a personalized training scheme for intracytoplasmic sperm injection (ICSI) through the use of learning curve-cumulative summation (LC-CUSUM), which allows to tailor training to the trainee performance, and to validate it against the performance of experienced embryologists.

Methods

Five trainees microinjected latex microspheres (LM) into vitro matured oocytes. A microinjection was considered successful when the oocyte did not lyse in the 24 h following the injection.

Results

Each trainee became proficient at ICSI after a variable number of injections, ranging from 35 to 80. Trainees that achieved proficiency went on to perform ICSI with human gametes in a clinical setting with proficiency comparable to that of experienced embryologists.

Conclusions

We show that LC-CUSUM based personalized ICSI training is feasible and allows trainees to be as proficient as trained embryologists when treating actual patients.

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Acknowledgments

The authors wish to thank Francesc Figueras for statistical support, Montserrat Barragán for help with figures composition, and the trainees for their participation in the study.

Author information

Authors and Affiliations

  1. Clinica EUGIN, Travessera de les Corts 322, 08029, Barcelona, Spain

    Mercè Durban, Albert Obradors, Valerie Vernaeve & Rita Vassena

  2. Fundació EUGIN, Travessera de les Corts 314, 08029, Barcelona, Spain

    Désireé García

Authors
  1. Mercè Durban
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  2. Désireé García
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  3. Albert Obradors
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  4. Valerie Vernaeve
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  5. Rita Vassena
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Corresponding author

Correspondence to Rita Vassena.

Ethics declarations

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Capsule A personalized training scheme for intracytoplasmic sperm injection (ICSI) through the use of learning curve-cumulative summation (LC-CUSUM) has been developed and evaluated to ensure that trainees exiting the program are as proficient at ICSI as trained embryologists.

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Durban, M., García, D., Obradors, A. et al. Are we ready to inject? Individualized LC-CUSUM training in ICSI. J Assist Reprod Genet 33, 1009–1015 (2016). https://doi.org/10.1007/s10815-016-0686-4

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  • DOI: https://doi.org/10.1007/s10815-016-0686-4

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