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Cytogenetic abnormalities in 179 cases with male infertility in Western Region of Turkey: Report and review

  • GENETICS
  • Published:
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Abstract

Purpose

In this study we aimed to evaluate the postnatally screened karyotype results in couples who were referred because of primary infertility between 2000 and 2006 in Izmir.

Methods

The records of a total of 179 cases were evaluated retrospectively.

Results

A total of 21 cases (11.74%) showed chromosomal alteration. Thirteen (7.26%) were 47,XXY; three (1.68%) were pericentric inversion of chromosome 9; one (0.56%) 46,XY/45,XO; one (0.56%) 46,XY/47,XXY/48,XXXY; one (0.56%) 46,XY,t(X;1); one (0.56%) 46,XY/46,XY,del(Y)(q11.2) and one (0.56%) 46,XX.

Conclusions

The rate of gonosomal chromosomal abnormalities was nearly three times higher in our region than the rate in the literature. Chromosomal analysis is strongly suggested particularly in those who suffer fertility problems.

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Acknowledgement

We would like to thank the cytogenetics staff of the Department of Medical Genetics.

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Authors and Affiliations

  1. Faculty of Medicine, Department of Medical Genetics, Ege University, Izmir, Turkey

    M. Akgul, F. Ozkinay, O. Cogulu & C. Ozkinay

  2. Faculty of Medicine, Department of Medical Genetics, Dokuz Eylul University, Izmir, Turkey

    D. Ercal

  3. Faculty of Medicine, Department of Medical Biology, Ege University, Izmir, Turkey

    O. Dogan & C. Gunduz

  4. Faculty of Medicine, Department of Urology, Ege University, Izmir, Turkey

    B. Altay

  5. Family Planning-Infertility Research and Treatment Center, Izmir, Turkey

    E. Tavmergen

Authors
  1. M. Akgul
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  2. F. Ozkinay
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  3. D. Ercal
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  4. O. Cogulu
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  5. O. Dogan
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  6. B. Altay
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  7. E. Tavmergen
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  8. C. Gunduz
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  9. C. Ozkinay
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Corresponding author

Correspondence to O. Cogulu.

Additional information

Capsule

The first report from west region of Turkey with a table showing a review of the literature and summarizing overall incidences.

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Akgul, M., Ozkinay, F., Ercal, D. et al. Cytogenetic abnormalities in 179 cases with male infertility in Western Region of Turkey: Report and review. J Assist Reprod Genet 26, 119–122 (2009). https://doi.org/10.1007/s10815-009-9296-8

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  • DOI: https://doi.org/10.1007/s10815-009-9296-8

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