Abstract
Respiratory sinus arrhythmia (RSA) is proposed to index cognitive and behavioral inflexibility. Broad autism phenotype (BAP) traits are prevalent in family members of children with autism spectrum disorder (ASD). The study investigated whether RSA and BAP traits in mothers of typically developing (TD) children and mothers of children with ASD influence maternal affect. It was hypothesized that these factors would interact to influence mother–child interactions. Twenty-three mother–child dyads participated in a challenging interaction while measuring mother’s RSA. Results indicated that mothers of children with ASD show different RSA reactivity than mothers of TD children. Furthermore, preliminary analyses revealed RSA reactivity moderated the relationship between mothers’ rigidity and maternal affect during this interaction. Implications for future research and interventions are discussed.
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References
Abidin, R. R. (2012). Parenting stress index, fourth edition: Professional manual. Odessa, FL: Psychological Assessment Resources Inc.
Allen, J. J., Chambers, A. S., & Towers, D. N. (2007). The many metrics of cardiac chronotropy: A pragmatic primer and a brief comparison of metrics. Biological Psychology,74(2), 243–262.
Austin, P. C., & Steyerberg, E. W. (2015). The number of subjects per variable required in linear regression analyses. Journal of Clinical Epidemiology,68(6), 627–636.
Beauchaine, T. (2001). Vagal tone, development, and Gray’s motivational theory: Toward an integrated model of autonomic nervous system functioning in psychopathology. Development and Psychopathology,13(2), 183–214.
Beauchaine, T. P., & Thayer, J. F. (2015). Heart rate variability as a transdiagnostic biomarker of psychopathology. International Journal of Psychophysiology,98(2 Pt 2), 338–350. https://doi.org/10.1016/j.ijpsycho.2015.08.004.
Benevides, T. W., & Lane, S. J. (2015). A review of cardiac autonomic measures: Considerations for examination of physiological response in children with autism spectrum disorder. Journal of Autism and Developmental Disorders,45(2), 560–575.
Berntson, G. G., Bigger, J. T., Jr., Eckberg, D. L., Grossman, P., Kaufmann, P. G., Malik, M., et al. (1997). Heart rate variability: Origins, methods, and interpretive caveats. Psychophysiology,34(6), 623–648.
Bögels, S. M., Lehtonen, A., & Restifo, K. (2010). Mindful parenting in mental health care. Mindfulness,1(2), 107–120.
Butler, E. A., Wilhelm, F. H., & Gross, J. J. (2006). Respiratory sinus arrhythmia, emotion, and emotion regulation during social interaction. Psychophysiology,43(6), 612–622.
Cachia, R. L., Anderson, A., & Moore, D. W. (2016). Mindfulness, stress and well-being in parents of children with autism spectrum disorder: A systematic review. Journal of Child and Family Studies,25(1), 1–14.
Cacioppo, J. T., Berntson, G. G., Malarkey, W. B., Kiecolt-Glaser, J. K., Sheridan, J. F., Poehlmann, K. M., … Glaser, R. (1998). Autonomic, neuroendocrine, and immune responses to psychological stress: the reactivity hypothesis. Annals of the New York Academy of Sciences, 840(1), 664–673.
Condy, E. E., Scarpa, A., & Friedman, B. H. (2017). Respiratory sinus arrhythmia predicts restricted repetitive behavior severity. Journal of Autism and Developmental Disorders,47, 1804–2795.
Constantino, J. N., & Gruber, C. P. (2012). Social responsiveness scale (2nd ed.). Los Angeles, CA: Western Psychological Services.
Davis, N. O., & Carter, A. S. (2008). Parenting stress in mothers and fathers of toddlers with autism spectrum disorders: Associations with child characteristics. Journal of Autism and Developmental Disorders,38(7), 1278–1291.
Estes, A., Olson, E., Sullivan, K., Greenson, J., Winter, J., Dawson, G., et al. (2013). Parenting-related stress and psychological distress in mothers of toddlers with autism spectrum disorders. Brain and Development,35(2), 133–138.
Factor, R. S., Swain, D. M., & Scarpa, A. (2018). Child autism spectrum disorder traits and parenting stress: The utility of using a physiological measure of parental stress. Journal of Autism and Developmental Disorders,48(4), 1081–1091.
Fortunato, C. K., Gatzke-Kopp, L. M., & Ram, N. (2013). Associations between respiratory sinus arrhythmia reactivity and internalizing and externalizing symptoms are emotion specific. Cognitive, Affective, & Behavioral Neuroscience, 13(2), 238–251.
Friedman, B. H. (2007). An autonomic flexibility–neurovisceral integration model of anxiety and cardiac vagal tone. Biological Psychology,74(2), 185–199.
Friedman, B. H., & Thayer, J. F. (1998a). Autonomic balance revisited: Panic anxiety and heart rate variability. Journal of Psychosomatic Research,44(1), 133–151.
Friedman, B. H., & Thayer, J. F. (1998b). Anxiety and autonomic flexibility: A cardiovascular approach. Biological Psychology,49(3), 303–323.
Gamelin, F. X., Berthoin, S., & Bosquet, L. (2006). Validity of the polar S810 heart rate monitor to measure R–R intervals at rest. Medicine and Science in Sports and Exercise,38, 887–893.
Garland, E. L., Froeliger, B., & Howard, M. O. (2014). Effects of mindfulness-oriented recovery enhancement on reward responsiveness and opioid cue-reactivity. Psychopharmacology,231(16), 3229–3238. https://doi.org/10.1007/s00213-014-3504-7.
Goodie, J. L., Larkin, K. T., & Schauss, S. (2000). Validation of the Polar heart rate monitor for assessing heart rate during physical and mental stress. Journal of Psychophysiology,14, 159–164.
Graziano, P., & Derefinko, K. (2013). Cardiac vagal control and children’s adaptive functioning: A meta-analysis. Biological Psychology,94(1), 22–37.
Grossman, P., Karemaker, J., & Wieling, W. (1991). Prediction of tonic parasympathetic cardiac control using respiratory sinus arrhythmia: The need for respiratory control. Psychophysiology,28(2), 201–216.
Grossman, P., & Taylor, E. W. (2007). Toward understanding respiratory sinus arrhythmia: Relations to cardiac vagal tone, evolution and biobehavioral functions. Biological Psychology,74(2), 263–285.
Harris, P., Taylor, R., Thielke, R., Payne, J., Gonzalez, N., & Conde, J. (2009). Research electronic data capture (REDCap): A metadata-driven methodology and workflow process for providing translational research informatics support. Journal of Biomedical Information,42(2), 377–381.
Hastings, P. D., Sullivan, C., McShane, K. E., Coplan, R. J., Utendale, W. T., & Vyncke, J. D. (2008). Parental socialization, vagal regulation, and preschoolers’ anxious difficulties: Direct mothers and moderated fathers. Child Development,79(1), 45–64.
Hudson, J. L., & Rapee, R. M. (2001). Parent–child interactions and anxiety disorders: An observational study. Behaviour Research and Therapy,39(12), 1411–1427.
Hurley, R. S. E., Losh, M., Parlier, M., Reznick, J. S., & Piven, J. (2007). The broad autism phenotype questionnaire. Journal of Autism and Developmental Disorders,37(9), 1679–1690. https://doi.org/10.1007/s10803-006-0299-3.
Jennings, J. R., Kamarck, T., Stewart, C., Eddy, M., & Johnson, P. (1992). Alternate cardiovascular baseline assessment techniques: Vanilla or resting baseline. Psychophysiology,29(6), 742–750.
Johnson, P. E. (2019). rockchalk: Regression estimation and presentation. R package version 1.8.144. https://CRAN.R-project.org/package=rockchalk.
Joo, H. M., Lee, S. J., Chung, Y. G., & Shin, I. Y. (2010). Effects of mindfulness based stress reduction program on depression, anxiety and stress in patients with aneurysmal subarachnoid hemorrhage. Journal of Korean Neurosurgical Society,47(5), 345–351. https://doi.org/10.3340/jkns.2010.47.5.345.
Kabat-Zinn, J., Chapman, A., & Salmon, P. (1997). Relationship of cognitive and somatic components of anxiety to patient preference for different relaxation techniques. Mind Body Medicine,2, 101–109.
Katz, L. F. (2007). Domestic violence and vagal reactivity to peer provocation. Biological Psychology,74(2), 154–164.
Larson, M. R., Ader, R., & Moynihan, J. A. (2001). Heart rate, neuroendocrine, and immunological reactivity in response to an acute laboratory stressor. Psychosomatic Medicine,63(3), 493–501.
Lehrer, P. M., Vaschillo, E., & Vaschillo, B. (2000). Resonant frequency biofeedback training to increase cardiac variability: Rationale and manual for training. Applied Psychophysiology and Biofeedback,25(3), 177–191.
Lehrer, P. M., Vaschillo, E., Vaschillo, B., Lu, S. E., Eckberg, D. L., Edelberg, R., … Hamer, R. M. (2003). Heart rate variability biofeedback increases baroreflex gain and peak expiratory flow. Psychosomatic Medicine, 65(5), 796–805.
Lo, H. H., Wong, S. Y., Wong, J. Y., Wong, S. W., & Yeung, J. W. (2016). The effect of a family-based mindfulness intervention on children with attention deficit and hyperactivity symptoms and their parents: Design and rationale for a randomized, controlled clinical trial (study protocol). BMC Psychiatry,16(1), 65.
Losh, M., Childress, D., Lam, K., & Piven, J. (2008). Defining key features of the broad autism phenotype: A comparison across parents of multiple-and single-incidence autism families. American Journal of Medical Genetics B,147(4), 424–433.
Matthews, K. A., Manuck, S. B., & Saab, P. G. (1986). Cardiovascular responses of adolescents during a naturally occurring stressor and their behavioral and psychophysiological predictors. Psychophysiology,23(2), 198–209.
McBride, B. A., Schoppe, S. J., & Rane, T. R. (2002). Child characteristics, parenting stress, and parental involvement: Fathers versus mothers. Journal of Marriage and Family,64(4), 998–1011.
Patron, E., Benvenuti, S. M., Favretto, G., Valfrè, C., Bonfa, C., Gasparotto, R., et al. (2013). Biofeedback assisted control of respiratory sinus arrhythmia as a biobehavioral intervention for depressive symptoms in patients after cardiac surgery: A preliminary study. Applied Psychophysiology and Biofeedback,38(1), 1–9.
Piven, J., Palmer, P., Jacobi, D., Childress, D., & Arndt, S. (1997). Broader autism phenotype: Evidence from a family history study of multiple-incidence autism families. American Journal of Psychiatry,154(2), 185–190. https://doi.org/10.1176/ajp.154.2.18.
Porges, S. W. (2007). The polyvagal perspective. Biological Psychology,74(2), 116–143.
R Core Team. (2013). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. Retrieved November 2017, from http://www.R-project.org/.
Sasson, N. J., Lam, K. S., Childress, D., Parlier, M., Daniels, J. L., & Piven, J. (2013). The broad autism phenotype questionnaire: Prevalence and diagnostic classification. Autism Research,6(2), 134–143.
Singh, N. N., Lancioni, G. E., Winton, A. S., Singh, J., Curtis, W. J., Wahler, R. G., et al. (2007). Mindful parenting decreases aggression and increases social behavior in children with developmental disabilities. Behavior Modification,31(6), 749–771.
Skowron, E. A., Cipriano-Essel, E., Gatzke-Kopp, L. M., Teti, D. M., & Ammerman, R. T. (2014). Early adversity, RSA, and inhibitory control: Evidence of children’s neurobiological sensitivity to social context. Developmental Psychobiology,56(5), 964–978.
Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. (1996). Heart rate variability: Standards of measurement, physiological interpretation, and clinical use. European Heart Journal,17, 354–381.
Thayer, J. F., Friedman, B. H., & Borkovec, T. D. (1996). Autonomic characteristics of generalized anxiety disorder and worry. Biological Psychiatry,39(4), 255–266.
Thayer, J. F., Hansen, A. L., Saus-Rose, E., & Johnsen, B. H. (2009). Heart rate variability, prefrontal neural function, and cognitive performance: The neurovisceral integration perspective on self-regulation, adaptation, and health. Annals of Behavioral Medicine,37(2), 141–153.
Thayer, J. F., & Lane, R. D. (2000). A model of neurovisceral integration in emotion regulation and dysregulation. Journal of Affective Disorders,61(3), 201–216.
Zucker, T. L., Samuelson, K. W., Muench, F., Greenberg, M. A., & Gevirtz, R. N. (2009). The effects of respiratory sinus arrhythmia biofeedback on heart rate variability and posttraumatic stress disorder symptoms: A pilot study. Applied Psychophysiology and Biofeedback,34(2), 135.
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RF & DS completed data collection procedures and supervised behavioral coding. EC, RF, DS, and MS were responsible for theory development and analysis of the data. EC, RF, DS, MS, & AS were responsible for the writing of the manuscript.
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Condy, E.E., Factor, R.S., Swain, D.M. et al. Maternal Affect During a Challenging Mother–Child Interaction: The Effects of Broad Autism Phenotype and Respiratory Sinus Arrhythmia Reactivity in Mothers of Children With and Without Autism Spectrum Disorder. J Autism Dev Disord 49, 4891–4900 (2019). https://doi.org/10.1007/s10803-019-04198-4
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DOI: https://doi.org/10.1007/s10803-019-04198-4