Abstract
There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services.
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14 March 2019
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Acknowledgments
We wish to sincerely thank the participants and their families for their valuable and long-lasting collaboration and their confidence in our study. We also extend our thanks to the research teams for their support during the past 15 years. A special thought to Florine Dellapiazza and to Colette Boy for their help with the literature review.
Funding
This work was supported by grants from the Orange Foundation, and the French national health institute (PHRC 1997 & 2007 and ANR Blanc).
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AB was involved in the study design and methods, data collection, interpretation of results, writing, and revision of the initial draft. EP was involved in the study design and methods and data collection. CM and CR were involved in data analysis, interpretation of results, writing, and revision of the draft. KM was involved in the interpretation, writing, and revision of the draft. All the authors have critically revised this article and approved the final version to be published.
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This study was approved by the Medical ethical committee and the National Commission for Computing and Liberties (CNIL. number 1585321 v0).
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Baghdadli, A., Rattaz, C., Michelon, C. et al. Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort. J Autism Dev Disord 49, 2243–2256 (2019). https://doi.org/10.1007/s10803-019-03901-9
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DOI: https://doi.org/10.1007/s10803-019-03901-9