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Electrochemical determination diethylstilbestrol by a single-walled carbon nanotube/platinum nanoparticle composite film electrode

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Abstract

Platinum nanoparticles (Ptnano) were prepared and used in combination with single-wall carbon nanotube (SWNT) for fabricating electrochemical sensors with remarkably improved sensitivity toward diethylstilbestrol (DES). The glassy carbon (GC) electrode modified with SWNT/Ptnano composite film exhibited excellent electrochemical behaviors toward the redox of DES. Compared with the bare GC electrode and SWNTs film modified GC electrode, the redox peak currents at the SWNTs/Ptnano composite film modified GC electrode was enhanced greatly. The experimental parameters, which influence the peak current of DES, were optimized. Under optimal conditions, a linear response of DES was obtained in the range from 1.0 × 10−7 to 2.0 × 10−5 mol L−1 (R = 0.997) and with a limit of detect (LOD) of 1.5 × 10−8 mol L−1. The proposed procedure was successfully applied to determine the active ingredient in the DES tablet with satisfactory results.

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Acknowledgement

This work was supported by the Key Project of Chinese Ministry of Education (No. 206104), the Open Project Program of Key Laboratory of Low Dimensional Materials & Application Technology (Xiangtan University), Ministry of Education, China (No. KF0501) and the Multidiscipline Scientific Research Foundation of Xiangtan University (05IND08).

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Authors and Affiliations

  1. Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, Hunan, 411105, PR China

    Junjie Fei, Xiaoqin Wen, Lanhua Yi, Fang Ge, Ying Zhang, Meihua Huang & Xiaoming Chen

  2. Key Laboratory of Low Dimensional Materials and Application Technology of Ministry of Education, Xiangtan University, Xiangtan, Hunan, 411105, China

    Junjie Fei

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  1. Junjie Fei
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  2. Xiaoqin Wen
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  4. Fang Ge
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  7. Xiaoming Chen
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Correspondence to Junjie Fei.

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Fei, J., Wen, X., Yi, L. et al. Electrochemical determination diethylstilbestrol by a single-walled carbon nanotube/platinum nanoparticle composite film electrode. J Appl Electrochem 38, 1527–1533 (2008). https://doi.org/10.1007/s10800-008-9597-0

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  • DOI: https://doi.org/10.1007/s10800-008-9597-0

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