Skip to main content

Advertisement

SpringerLink
Log in

Diurnal variation of anterior segment parameters handled with Scheimpflug imaging in keratoconus patients

  • Original Paper
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To define diurnal changes in anterior segment parameters of keratoconus patients by using Scheimpflug imaging.

Methods

All keratoconus patients had corneal topography measurements 3 times a day (around 09:00 AM, 13:00 PM and 17:00 PM) by the same experienced operator. Three consecutive scans in each measurement session were obtained. The average of three measurements was used for analysis. A repeated measures analysis of variance with one within-subject factor (time of day) was carried out to assess diurnal variation.

Results

This study included 26 eyes of 26 patients with keratoconus. Significant diurnal variation was found in CCT and TCT measurements (P < 0.01, and P < 0.01, respectively). The mean amplitudes of change in CCT and TCT were 4.2 ± 1 µm (95% CI: 1.7–6.8 µm) and 4.1 ± 1.1 µm (95% CI: 1.2–8.0 µm), while the mean of CCT and TCT were 462.4 ± 34.5 µm (95% CI: 448.4–476.6 µm) and 452.9 ± 6.6 µm (95% CI: 439.3–466.5 µm), respectively. The maximum value and the lowest value were observed at 09:00 AM and at 17:00 PM, respectively. Other parameters except CCT and TCT did not show diurnal variation.

Conclusion

Statistically significant but clinically insignificant diurnal variation in CCT and TCT measurements of the keratoconus patients were detected over an 8-hour period (09:00 AM–17:00 PM).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Gomes JAP, Tan D, Rapuano CJ et al (2015) Global consensus on keratoconus and ectatic diseases. Cornea 34:359–369

    Article  Google Scholar 

  2. Henriquez M, Izquierdo L, Bernilla C et al (2011) Riboflavin/Ultraviolet A corneal collagen cross-linking for the treatment of keratoconus: visual outcomes and Scheimpflug analysis. Cornea 30:281–286

    Article  Google Scholar 

  3. Hashemi H, Seyedian MA, Miraftab M et al (2013) Corneal collagen crosslinking with riboflavin and ultraviolet a irradiation for keratoconus: longterm results. Ophthalmology 120:1515–1520

    Article  Google Scholar 

  4. Poli M, Cornut PL, Balmitgere T et al (2013) Prospective study of corneal collagen cross-linking efficacy and tolerance in the treatment of keratoconus and corneal ectasia: 3-year results. Cornea 32:583–590

    Article  Google Scholar 

  5. Shetty R, Pahuja NK, Nuijts RM et al (2015) Current protocols of corneal collagen cross-linking: visual, refractive, and tomographic outcomes. Am J Ophthalmol 160:243–249

    Article  Google Scholar 

  6. Vinciguerra R, Romano MR, Camesasca FI et al (2013) Corneal cross-linking as a treatment for keratoconus: four-year morphologic and clinical outcomes with respect to patient age. Ophthalmology 5(120):908–916

    Article  Google Scholar 

  7. Caporossi A, Mazzotta C, Paradiso AL et al (2013) Transepithelial corneal collagen crosslinking for progressive keratoconus: 24-month clinical results. J Cataract Refract Surg 39:1157–1163

    Article  Google Scholar 

  8. de Luis EB, Escudero Argaluza J, Pijoán Zubizarreta JI et al (2017) Evaluation of the reliability and repeatability of Scheimpflug system measurement in keratoconus. Cornea 32(2):177–181

    Google Scholar 

  9. Read SA, Collins MJ, Iskander DR (2008) Diurnal variation of axial length, intraocular pressure, and anterior eye biometrics. Invest Ophthalmol Vis Sci 49:2911–2918

    Article  Google Scholar 

  10. Read SA, Collins MJ (2009) Diurnal variation of corneal shape and thickness. Optom Vis Sci 86:170–180

    Article  Google Scholar 

  11. Shen M, Wang J, Qu J et al (2008) Diurnal variation of ocular hysteresis, corneal thickness, and intraocular pressure. Optom Vis Sci 85:1185–1192

    Article  Google Scholar 

  12. Hamilton KE, Pye DC, Aggarwala S et al (2007) Diurnal variation of central corneal thickness and Goldmann applanation tonometry estimates of intraocular pressure. J Glaucoma 16:29–35

    Article  Google Scholar 

  13. Shwrwin T, Brooks NH (2004) Morphological changes in keratoconus: pathology or pathogenesis. Clin Exp Ophthalmol 32(2):211–217

    Article  Google Scholar 

  14. Collier SA (2001) Is the corneal degradation in keratoconus caused by metalloproteinases? Clin Exp Ohthalmol 29(6):340–344

    Article  CAS  Google Scholar 

  15. Mackiewitz Z, Maatta M, Stenman M et al (2006) Collegenolytic proteinases in keratoconus. Cornea 25(5):603–610

    Article  Google Scholar 

  16. Mertz GW (1980) Overnight swelling of the living human cornea. J Am Optom Assoc 51:211–214

    CAS  PubMed  Google Scholar 

  17. Du Toit R, Vega JA, Fonn D et al (2003) Diurnal variation of corneal sensitivity and thickness. Cornea 22:205–209

    Article  Google Scholar 

  18. Duench S, Simpson T, Jones LW et al (2007) Assessment of variation in bulbar conjunctival redness, temperature, and blood flow. Optom Vis Sci 84:511–516

    Article  Google Scholar 

  19. Rabsilber TM, Khoramnia R, Auffarth GU (2006) Anterior chamber measurements using Pentacam rotating Scheimpflug camera. J Cataract Refract Surg 32:456–459

    Article  Google Scholar 

Download references

Funding

All authors state that they have no source of funding.

Author information

Authors and Affiliations

  1. Ophthalmology Department, Kayseri City Education and Research Hospital, Building of Pschiatry 1st Floor Ophthalmology Service, Kocasinan, Kayseri, Turkey

    Ayşe Çiçek, Atılım Armağan Demirtaş, Cemal Özsaygılı, Zeynep Duru, Döndü Melek Ulusoy, Necati Duru, Mahmut Erkam Arslan & Hayrettin Çobanoğlu

Authors
  1. Ayşe Çiçek
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Atılım Armağan Demirtaş
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Cemal Özsaygılı
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zeynep Duru
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Döndü Melek Ulusoy
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Necati Duru
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Mahmut Erkam Arslan
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Hayrettin Çobanoğlu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ayşe Çiçek.

Ethics declarations

Conflict of interest

All authors state that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Çiçek, A., Demirtaş, A.A., Özsaygılı, C. et al. Diurnal variation of anterior segment parameters handled with Scheimpflug imaging in keratoconus patients. Int Ophthalmol 40, 1481–1485 (2020). https://doi.org/10.1007/s10792-020-01315-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-020-01315-6

Keywords

Search

Navigation