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Ocular manifestations in celiac disease: an overview

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A Correction to this article was published on 02 April 2020

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Abstract

Purpose

To review and highlight the ocular manifestations associated with celiac disease (CD) and presentation of their pathogenetic mechanisms.

Methods

A thorough review of the literature was performed using PubMed to identify articles about serrated polyposis syndrome. The search was performed using the search string: (“celiac disease” OR “coeliac disease”) AND (“ocular manifestations” OR “eye” OR “orbitopathy” OR “uveitis” OR “neuro-ophthalmic manifestations”). Only articles in English were reviewed.

Results

Several ocular symptoms and disorders have been associated with CD and are a result of defective intestinal absorption and immunological mechanisms. These include nyctalopia, dry eye, cataract, thyroid-associated orbitopathy, uveitis, central retinal vein occlusion and neuro-ophthalmic manifestations. In addition, CD-related ocular disease may represent the first manifestation of CD.

Conclusion

CD may hold accountable for the development of ocular diseases of obscure etiology.

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Change history

  • 02 April 2020

    In the original publication, first line of <Emphasis Type="Italic">methods</Emphasis> under the Abstract section was published incorrectly.

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, School of Health Sciences, University Hospital of Ioannina, University of Ioannina, 45100, Ioannina, Greece

    Fotios S. Fousekis, Konstantinos H. Katsanos & Dimitrios K. Christodoulou

  2. Department of Ophthalmology, School of Health Sciences, University Hospital of Ioannina, University of Ioannina, Ioannina, Greece

    Andreas Katsanos

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  1. Fotios S. Fousekis
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Correspondence to Dimitrios K. Christodoulou.

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Fousekis, F.S., Katsanos, A., Katsanos, K.H. et al. Ocular manifestations in celiac disease: an overview. Int Ophthalmol 40, 1049–1054 (2020). https://doi.org/10.1007/s10792-019-01254-x

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