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The optokinetic response is effective to assess objective visual acuity in patients with cataract and age-related macular degeneration

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Abstract

Purpose

To estimate objective visual acuity in subjects suffering from cataract and age-related macular degeneration via the optokinetic response evoked by a non-conventional induction method (oktotype); in addition, to compare such objective outcome with the subjective acuity based on the ETDRS charts.

Methods

Patients were presented with 13 sequences of symbols arranged horizontally to form a serial pattern, moving from left to right at a constant rate. In each sequence, the size of the stimuli was reduced progressively, while the operator checked for the disappearance of the optokinetic response via a small video camera mounted on the test lens frame. The minimum angular size of the serial pattern able to evoke the optokinetic response (MAER) was referred to as the objective visual acuity of the subject.

Results

Correlation between logMAER and logMAR was significant in the cataract and macular degeneration group (\(R_{\text{cat}}^{2}\) = 0.70, p < .0001; \(R_{\text{AMD}}^{2}\) = 0.63, p < .0007). In the two samples, the correspondence between subjective and objective visual acuity (as, respectively, decimal units and arbitrary decimal units) was satisfactory (concordance correlation coefficient: cataract group = 0.91 and AMD group = 0.93). Test–retest reliability of the oktotype was good for the cataract group and moderate for the AMD sample (Κ 0.81 and 0.59, respectively).

Conclusion

The oktotype seems a promising tool to objectively assess visual acuity in noncooperating subjects with cataract or macular degeneration. Further research on other clinical conditions is needed to clarify the suitability of the procedure in the clinical setting.

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Notes

  1. We are grateful to the anonymous reviewer for this valuable suggestion.

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Authors and Affiliations

  1. Department of Ophthalmology, Service of Orthoptics, Molinette Hospital, University of Turin, Via Cherasco 23, 10126, Turin, Italy

    Carlo Aleci, Gabriele Cossu & Lorenzo Canavese

  2. Service of Neuro-Ophthalmology, Ophthalmic Hospital, Via Juvarra 19, 10100, Turin, Italy

    Carlo Aleci, Gabriele Cossu & Lorenzo Canavese

  3. Department of Pediatric Ophthalmology, Service of Orthoptics, Ophthalmic Hospital, Via Juvarra 19, 10100, Turin, Italy

    Elena Belcastro

Authors
  1. Carlo Aleci
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  2. Gabriele Cossu
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  3. Elena Belcastro
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  4. Lorenzo Canavese
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Correspondence to Carlo Aleci.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Aleci, C., Cossu, G., Belcastro, E. et al. The optokinetic response is effective to assess objective visual acuity in patients with cataract and age-related macular degeneration. Int Ophthalmol 39, 1783–1792 (2019). https://doi.org/10.1007/s10792-018-1001-4

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  • DOI: https://doi.org/10.1007/s10792-018-1001-4

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